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Official Full Name nudE nuclear distribution gene E homolog 1 (A. nidulans)
Background This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Alternative splicing results in multiple transcript variants.
Synonyms NDE1; nudE nuclear distribution gene E homolog 1 (A. nidulans); nuclear distribution protein nudE homolog 1; FLJ20101; NUDE; HOM TES 87; LIS1 interacting protein NUDE1rat homolog; LIS1 interacting protein NUDE1; NDE 1; NDE1_HUMAN; Nuclear distribution gene E homolog 1; NUDE 1; NudE nuclear distribution gene E homolog 1; NUDE1; OTTHUMP00000160329; OTTHUMP00000160330; LIS1-interacting protein NUDE1, rat homolog; LIS4; HOM-TES-87
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NDE1-1218H Recombinant Human NDE1, GST-tagged E.coli GST
    Human NDE1-28795TH Recombinant Human NDE1, His-tagged E.coli His
    Human NDE1-3514H Recombinant Human NDE1, His-tagged E.coli His
    Human NDE1-3938HCL Recombinant Human NDE1 293 Cell Lysate HEK293 N/A
    Mouse NDE1-10494M Recombinant Mouse NDE1 Protein Mammalian Cell His
    Rat NDE1-3926R Recombinant Rat NDE1 Protein Mammalian Cell His
    Rhesus Macaque NDE1-2964R Recombinant Rhesus monkey NDE1 Protein, His-tagged Mammalian Cell His
    Chicken NDE1-1319C Recombinant Chicken NDE1 Mammalian Cell His
    Zebrafish NDE1-3303Z Recombinant Zebrafish NDE1 Mammalian Cell His

    NDE1 involved in several pathways and played different roles in them. We selected most pathways NDE1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Anchoring of the basal body to the plasma membrane CETN2; B9D1; TCTN3; CEP97; CEP135; ACTR1A; TSGA14; CEP89; CSNK1E; CSNK1D
    Assembly of the primary cilium NPHP4; KIF3C; BBS7; CCDC123; BBS13; FLR; DYNLRB2; B9D1; AKAP9; BBS2
    Cell Cycle, Mitotic CEP290; CEP63; STAG1; KIF18A; MAPRE1A; LMNB1; CETN2; CENPA; NIPBL; HAUS2
    Centrosome maturation OFD1; TUBB4B; CSNK1E; CSNK1D; ACTR1A; NDE1; DYNC1H1; CEP135; MAPRE1A; CLASP1A
    G2/M Transition SSNA1; CEP57; ODF2; MAPRE1; CDK11A; TUBGCP3; CEP78; CEP152; LIN9; TUBG2
    Loss of Nlp from mitotic centrosomes CEP135; PCM1; MAPRE1A; ODF2; CEP63; CEP164; CEP76; CEP152; CEP70; MAPRE1
    Loss of proteins required for interphase microtubule organizationfrom the centrosome CEP72; MAPRE1B; CCP110; CEP135; CLASP1A; MAPRE1; NINL; CEP164; NEDD1; ODF2B

    NDE1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by NDE1 itself. We selected most functions NDE1 had, and list some proteins which have the same functions with NDE1. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding EPS15; CHAF1A; GOT2A; PHC2; PARK7; GNPNAT1; RABAC1; TTR; ECI1; YWHAZ
    microtubule binding FAM83D; EZR; AKAP1; MTAP7D3; KIF5AA; WDR81; KIF11; GOLSYN; CHD4; KATNA1
    protein binding KLF17; RUFY3; CXorf40A; HIST1H4E; NTSR1; PTRF; SCLY; TRPV4; SRPK1; PKD2
    protein domain specific binding ARL1; TJP1; STXBP1; IGBP1; HOXB1; MPP5; STMN3; VPS4A; WNT3; TWIST2

    NDE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDE1.

    Pafah1b1; ZNF365; CDK1; CENPF; Nde1; q81ks6_bacan; Ccser2; AMZ2; APIP; LCOR; CLPTM1L; DCAF13

    Lee, JY; Kang, CD; et al. Engineering Cellular Redox Balance in Saccharomyces cerevisiae for Improved Production of L-Lactic Acid. BIOTECHNOLOGY AND BIOENGINEERING 112:751-758(2015).
    Okamoto, M; Iguchi, T; et al. DBZ Regulates Cortical Cell Positioning and Neurite Development by Sustaining the Anterograde Transport of Lis1 and DISC1 through Control of Ndel1 Dual-Phosphorylation. JOURNAL OF NEUROSCIENCE 35:2942-2958(2015).

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