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NME4

  • Official Full Name

    non-metastatic cells 4, protein expressed in

  • Overview

    The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of;gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates.;The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997 (PubMed 9099850)).
  • Synonyms

    NME4; non-metastatic cells 4, protein expressed in; nucleoside diphosphate kinase, mitochondrial; nm23 H4; NM23H4; NDK; NDPKD; NDP kinase D; NDP kinase, mitochondrial; nucleoside diphosphate kinase D; NDPK-D; nm23-H4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NME4-196H Active Recombinant Human NME4 protein, His-tagged E.coli His
Human NME4-795H Recombinant Human NME4, His-tagged E.coli His
Human NME4-1313H Recombinant Human NME4, GST-tagged E.coli GST 1-187aa
Human NME4-28746TH Recombinant Human NME4, His-tagged E.coli His 155 amino acids
Human NME4-3789HCL Recombinant Human NME4 293 Cell Lysate HEK293 N/A
Human NME4-6578HF Recombinant Full Length Human NME4 Protein, GST-tagged In Vitro Cell Free System GST 187 amino acids
Human NME4-5930H Recombinant Human NME4 Protein, GST-tagged Wheat Germ GST
Human NME4-4713H Recombinant Human NME4 Protein (Thr67-His185), N-His tagged E.coli N-His Thr67-His185
Human NME4-5453H Recombinant Human NME4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse NME4-10741M Recombinant Mouse NME4 Protein Mammalian Cell His
Mouse Nme4-4437M Recombinant Mouse Nme4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Nme4-1763M Recombinant Mouse Nme4 protein, His & T7-tagged E.coli His/T7 Thr39~Leu172 (Accession # Q9WV84)
Mouse NME4-6111M Recombinant Mouse NME4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NME4-6111M-B Recombinant Mouse NME4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque NME4-3056R Recombinant Rhesus monkey NME4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NME4-2875R-B Recombinant Rhesus Macaque NME4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque NME4-2875R Recombinant Rhesus Macaque NME4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish NME4-11412Z Recombinant Zebrafish NME4 Mammalian Cell His
Chicken NME4-5441C Recombinant Chicken NME4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NME4 involved in several pathways and played different roles in them. We selected most pathways NME4 participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NME4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismENTPD6;PDE5A;NT5C1AA;POLR3E;DCK;NT5C2;GC3;NUDT2;POLR2J2
Pyrimidine metabolismNT5C;DTYMK;POLR1A;POLA2;DHODH;RRM1;POLR2J;POLR2A;NT5C1B-RDH14
Metabolic pathwaysIDH2;HMBSB;PYCR2;NDUFV1;ANPEPB;PLA2G12B;NDUFAB1;SEPHS2;MTMR3

NME4 has several biochemical functions, for example, ATP binding, lipid binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NME4 itself. We selected most functions NME4 had, and list some proteins which have the same functions with NME4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMAP3K1;CLK4;GTF2F2B;KIF15;PRKAG3;Abca2;MAPK12B;ILK;ASNS
lipid bindingFFAR1;EPN2;MELK;STARD13;ACOT12;PAQR5B;CADPS;CRABP2A;HDLBP
metal ion bindingPPP1CB;EPT1;COL9A1;PLA2G4AA;BMP1B;RNF220A;SNAI1B;ATP2B1;CTDSP2
nucleoside diphosphate kinase activityTXNDC3;AK4;NME6;NME8;AK5;NME9;CMPK2;NME2A;NME2B.2
protein bindingPLEKHF1;TCEAL5;ESRRA;PLSCR1;OLFM2;PLLP;ZIC3;MKRN1;PPP1R1A

NME4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NME4 here. Most of them are supplied by our site. Hope this information will be useful for your research of NME4.

NME1; CLNK; TNS4; HTT; SOCS3; LSM8; NME2; TRIP13; SUV39H2; ssrna_au; NSS; ICT1

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