NDUFA8 Protein, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa

NDUFA8

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NDUFA8

Official Full Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
Background The protein encoded by this gene belongs to the complex I 19 kDA subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Synonyms NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 (19kD, PGIV); NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; complex I PGIV subunit; MGC793; PGIV; complex I-19kD; c
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NDUFA8-1226H Recombinant Human NDUFA8, GST-tagged E.coli GST
    Human NDUFA8-129H Recombinant Human NDUFA8 Protein, His-tagged E.coli His
    Human NDUFA8-3915HCL Recombinant Human NDUFA8 293 Cell Lysate HEK293 N/A
    Mouse NDUFA8-10522M Recombinant Mouse NDUFA8 Protein Mammalian Cell His
    Chicken NDUFA8-5033C Recombinant Chicken NDUFA8 Mammalian Cell His
    Chicken NDUFA8-5034C Recombinant Chicken NDUFA8 Mammalian Cell His
    Zebrafish NDUFA8-10991Z Recombinant Zebrafish NDUFA8 Mammalian Cell His

    NDUFA8 involved in several pathways and played different roles in them. We selected most pathways NDUFA8 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylation COX5AA; SDHA; NDUFA12; ATP6V0D2; UQCRB; COX5A; ATP5G3; COX7A1; UQCRC2B; NDUFV2
    Metabolic pathways GATM; ATP5C1; SHMT1; MUT; ST6GALNAC4; NME6; IDH3G; AOC2; ACSM3; DPAGT1
    Non-alcoholic fatty liver disease (NAFLD) PRKAG2; BAX; IL6; NDUFA10; UQCRQ; PPARA; COX8C; MAP3K11; NDUFB1; COX7B
    Alzheimers disease Casp3; ADAM17; ATP5E; PPP3CB; UQCRFS1; GRIN2A; CASP12; NDUFB9; NDUFB8; NDUFS1
    Parkinsons disease NDUFB1; NDUFV2; SEPT5; UBE2L3; MT-ATP6; ATP5O; ATP5D; SDHB; NDUFA4L2; VDAC1
    Huntingtons disease PLCB3; POLR2K; SLC25A5; UQCR10; MT-ATP6; NDUFB8; TFAM; NDUFS5; COX4I2; NDUFA12

    NDUFA8 has several biochemical functions, for example, NADH dehydrogenase (ubiquinone) activity, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFA8 itself. We selected most functions NDUFA8 had, and list some proteins which have the same functions with NDUFA8. You can find most of the proteins on our site.

    Function Related Protein
    NADH dehydrogenase (ubiquinone) activity NDUFS6; NDUFS4; NDUFAF2; NDUFV3; NDUFS5; NDUFV1; NDUFA1; NDUFA13; NDUFV2; NDUFC1
    protein complex binding LCK; THRA; EP300; TULP2; AP2A2; SLC9A3R1; NDUFA4; DAG1; NR0B2; SH2B3

    NDUFA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFA8.

    NDUFA2; NDUFS3; TBC1D4; MYC; RAB7A; NDUFA6; ATM; KLC3; P; NDUFA11; CNTROB; NDUFAF3; TIMMDC1; GOLT1B

    Jesinkey, SR; Korrapati, MC; et al. Atomoxetine Prevents Dexamethasone-Induced Skeletal Muscle Atrophy in Mice. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 351:663-673(2014).
    Garrett, SM; Whitaker, RM; et al. Agonism of the 5-Hydroxytryptamine 1F Receptor Promotes Mitochondrial Biogenesis and Recovery from Acute Kidney Injury. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 350:257-264(2014).

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