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NDUFV3

Official Full Name

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
Overview

The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms

NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa; NADH dehydrogenase (ubiquinone) flavoprotein 3 (10kD); NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; CI 10k; complex I 10kDa subunit; CI-10k; CI-9kD; complex I, mitochondrial respiratory chain, 10-kD subunit; Complex I-9kD; mitochondrial NADH oxidoreductase-like protein; NADH ubiquinone oxidoreductase 9 kD subunit; NADH-ubiquinone oxidoreductase 9 kDa subunit; NADH-ubiquinone oxidoreductase flavoprotein 3, 10kD; NDUV3_HUMAN; Renal carcinoma antigen NY-REN-4; NADH-ubiquinone oxidoreductase 9 kD subunit;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NDUFV3-2345H	Recombinant Human NDUFV3, His-tagged	E.coli	His	97aa	Inquiry
Human	NDUFV3-1245H	Recombinant Human NDUFV3, GST-tagged	E.coli	GST	1-108aa	$319 / 25ug
Human	NDUFV3-3890HCL	Recombinant Human NDUFV3 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	NDUFV3-10550M	Recombinant Mouse NDUFV3 Protein	Mammalian Cell	His		Inquiry
Mouse	NDUFV3-5996M	Recombinant Mouse NDUFV3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Ndufv3-4350M	Recombinant Mouse Ndufv3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	NDUFV3-5996M-B	Recombinant Mouse NDUFV3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	NDUFV3-3947R	Recombinant Rat NDUFV3 Protein	Mammalian Cell	His		Inquiry
Rat	NDUFV3-3605R-B	Recombinant Rat NDUFV3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	NDUFV3-3605R	Recombinant Rat NDUFV3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Chicken	NDUFV3-4243C	Recombinant Chicken NDUFV3	Mammalian Cell	His		Inquiry
Chicken	NDUFV3-4244C	Recombinant Chicken NDUFV3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NDUFV3 involved in several pathways and played different roles in them. We selected most pathways NDUFV3 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFV3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Oxidative phosphorylation	NDUFB4;ATP6V1E2;ATP5H;Atp5k;NDUFB2;ATP6V0A1B;ATP6V0A4;ATP5C1;ATP5IB
Metabolic pathways	PIP5K1AA;CMPK2;CYP19A1A;MTMR7A;AKR1D1;MTMR7B;ST3GAL4;PLA2G1B;UGT2A3
Non-alcoholic fatty liver disease (NAFLD)	INS;NDUFA12;GSK3B;NFKB1;TGFB1;COX7A2L;NDUFC1;ITCH;MAP3K5
Alzheimers disease	Atp5g2;ATP5A1;CDK5R1;SDHD;NDUFA2;NDUFV3;ATP5D;NDUFAB1;COX7A2
Parkinsons disease	NDUFS3;NDUFS6;NDUFS8;PRKACB;NDUFS5;NDUFC2-KCTD14;UBA1;UBE2L3;NDUFA11
Huntingtons disease	BBC3;DNAH5;TBPL2;COX7A2;SLC25A5;PLCB1;TAF4B;ATP5J;HDAC1

NDUFV3 has several biochemical functions, for example, NADH dehydrogenase (ubiquinone) activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFV3 itself. We selected most functions NDUFV3 had, and list some proteins which have the same functions with NDUFV3. You can find most of the proteins on our site.

Function	Related Protein
NADH dehydrogenase (ubiquinone) activity	NDUFB1;NDUFC2-KCTD14;NDUFA9;NDUFS3;NDUFB7;NDUFS6;NDUFA5;NDUFB2;NDUFA8
poly(A) RNA binding	BUD13;UBFD1;PUM1;FAM98B;HNRNPH2;MFAP1;EXOSC10;SPTBN1;ETF1A

NDUFV3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFV3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFV3.

NDUFA2; PHYHIP; NDUFS4; NDUFS5; NDUFS6; NDUFS3; NDUFV2; NDUFV1; NDUFA6; NDUFA9; NDUFA11; TIMMDC1; NDUFA12