Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

NEDD4L

  • Official Full Name

    neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

  • Overview

    NEDD4 (neural precursor expressed, developmentally down-regulated protein 4) was originally identified as a gene that is highly expressed in the early mouse embryonic central nervous system. Subsequently, a family of NEDD4-like proteins have been defined
  • Synonyms

    NEDD4L; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down regulated 4 like; E3 ubiquitin-protein ligase NEDD4-like; KIAA0439; NEDD4 2; RSP5; ubiquitin;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • C
  • Myc
  • DDK
  • His
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NEDD4L-3885HCL Recombinant Human NEDD4L 293 Cell Lysate HEK293 N/A
Human NEDD4L-034H Recombinant Human NEDD4L Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human NEDD4L-4142H Recombinant Human NEDD4L Protein (Glu629-Asp975), N-His tagged E.coli N-His Glu629-Asp975
Human NEDD4L-0438H Recombinant Human NEDD4L Protein (A2-D975), Tag Free E.coli No tag A2-D975
Human NEDD4L-0439H Recombinant Human NEDD4L Protein (A2-D975), His tagged E.coli His A2-D975
Mouse Nedd4l-4360M Recombinant Mouse Nedd4l Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NEDD4L Related Research Area

NEDD4L involved in several pathways and played different roles in them. We selected most pathways NEDD4L participated on our site, such as Ubiquitin mediated proteolysis, Endocytosis, Aldosterone-regulated sodium reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEDD4L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ubiquitin mediated proteolysisCUL2;UBE1Y1;ANAPC7;ANAPC2;UBE2D1A;UBE2L3A;SIAH2L;CBL;UBE2A
EndocytosisGRK7A;ADRB3B;CHMP6B;ARPC5B;BF1;HRASA;KIF5A;CLTCB;WIPF1A
Aldosterone-regulated sodium reabsorptionNEDD4L;MAPK3;MAPK1;INS;PIK3CA;ATP1B4;ATP1B1;ATP1A3;ATP1B2

NEDD4L has several biochemical functions, for example, ion channel binding, ligase activity, potassium channel inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NEDD4L itself. We selected most functions NEDD4L had, and list some proteins which have the same functions with NEDD4L. You can find most of the proteins on our site.

Function Related Protein
ion channel bindingSUMO1;FGF13;ACTN4;DLG1;KCNIP2;FKBP1A;RYR2;YWHAE;KCNH5
ligase activityPCXB;MARCH4;RLIM;TOPORS;MARCH5;BARD1;ZSWIM2;COP1;TRIM22
potassium channel inhibitor activityNEDD4L;PTI;RASA1;KCNK2;KCNA5;CAV3;ENSA
potassium channel regulator activityKCNIP3;AKAP9;KCNIP1;DPP10;DLG1;SGK3;KCNMB3;KCNE1L;ABCC9
protein bindingHMGN4;PRRG2;FAM126B;LRRFIP1;C2orf50;TIA1;NFE2L2;CTSL1;DNAJB5
sodium channel inhibitor activityCAMK2D;PCSK9;SCN1B;SLC14A2;NEDD4L;NEDD4
sodium channel regulator activitySGK2B;FXYD1;SGK3;FXYD5;NEDD4L;SCN1B;SCN1BA;FXYD3;PRSS30
ubiquitin protein ligase activitySIAH1;CBLC;UBR3;HACE1;RNF13;RNF146;RNF217;ANAPC11;RNF6
ubiquitin-protein transferase activityLNX1;UBE2M;HECW1B;RLIM;UBE2S;NHLRC1;PJA2;RNF151;MARCH4

NEDD4L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEDD4L here. Most of them are supplied by our site. Hope this information will be useful for your research of NEDD4L.

DAZAP2; SCNN1B; RAPGEF2; AMOT; MED28; FBXL15; ARHGDIA; YWHAG; LAPTM5; SMAD2; GORAB; WNK1; AATF; RNF11; vpr; YWHAH; TOLLIP

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All NEDD4L Products

Required fields are marked with *

My Review for All NEDD4L Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends