NEK8
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Official Full Name
NIMA (never in mitosis gene a)-related expressed kinase 8
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Overview
This gene encodes a NIMA-related kinase. Members of this serine/threonine protein kinase family are structurally-related to NIMA (never in mitosis, gene A) which controls mitotic signaling in Aspergillus nidulans. -
Synonyms
NEK8; NIMA (never in mitosis gene a)-related expressed kinase 8; serine/threonine-protein kinase Nek8; JCK; NEK 8; NEK12A; NEK8_HUMAN; Never in mitosis A-related kinase 8; NIMA-family kinase NEK8; NIMA-related kinase 12a; Nima-related protein kinase 12a; NimA-related protein kinase 8; juvenile cystic kidney; NIMA-related expressed kinase 8; 4632401F23Rik;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NEK8-1184HCL | Recombinant Human NEK8 cell lysate | N/A |
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| Rat | NEK8-3956R | Recombinant Rat NEK8 Protein | Mammalian Cell | His |
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| Rat | NEK8-3614R | Recombinant Rat NEK8 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | NEK8-3614R-B | Recombinant Rat NEK8 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | NEK8-9400Z | Recombinant Zebrafish NEK8 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
NEK8 involved in several pathways and played different roles in them. We selected most pathways NEK8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NEK8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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NEK8 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEK8 itself. We selected most functions NEK8 had, and list some proteins which have the same functions with NEK8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | TRIO;RUNX2A;CAMK1;AKT1;STK31;TAOK3;DDX19;PIM1;PKN1 |
| metal ion binding | PVALB2;ZNF576.2;POMT1;CACNA2D4;HEPHL1A;FOXP2;ZFP13;SMAP2;ASGR1 |
| protein binding | DHX15;RHOV;SERP2;THBD;H3F3C;COG8;MRPL12;TMED2;NFYB |
| protein serine/threonine kinase activity | STK38L;CSNK1G1;ULK4;ACVR1;SGK1;MAPK14;AURKA;EIF2AK3;SIK3 |
NEK8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEK8 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEK8.
TCF4; TRIM69; ABL1; FYN; HSP90AB1; NCK1; GRB2; NUDCD2
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