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NID2

  • Official Full Name

    nidogen 2

  • Overview

    Nidogen-2 is a protein that in humans is encoded by the NID2 gene. Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM 142461), and nidogen (see NID1; MIM 131390), are thin pericellular protein matrices that control a large number of cellular activities, including adhesion, migration, differentiation, gene expression, and apoptosis.[supplied by OMIM
  • Synonyms

    Nid2; nidogen2; Ly111; NID-2; AW547149; nidogen-2; entactin-2; osteonidogen2; nidogen 2 (osteonidogen);

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NID2-1195HCL Recombinant Human NID2 cell lysate N/A
Human NID2-224H Recombinant Human NID2 Protein, His-tagged E.coli His Leu31~Ala289
Human NID2-4120H Recombinant Human NID2 Protein (Gly1107-Gly1373), N-His tagged E.coli N-His Gly1107-Gly1373
Mouse Nid2-612M Active Recombinant Mouse Nid2 Protein, His-tagged Mammalian cells His Leu31-Lys1403
Mouse NID2-10662M Recombinant Mouse NID2 Protein Mammalian Cell His
Mouse Nid2-6063M Recombinant Mouse Nid2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nid2-6063M-B Recombinant Mouse Nid2 Protein Pre-coupled Magnetic Beads HEK293
Rat NID2-3987R Recombinant Rat NID2 Protein Mammalian Cell His
Rat NID2-3646R Recombinant Rat NID2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NID2-3646R-B Recombinant Rat NID2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NID2 Related Articles

NID2 involved in several pathways and played different roles in them. We selected most pathways NID2 participated on our site, such as Extracellular matrix organization, Laminin interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with NID2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Extracellular matrix organizationCOL9A1;COL25A1;TPSAB1;TLDC2;ADAM8;COL17A1A;COL8A2;BGNB;COL6A3
Laminin interactionsLAMB1B;NID2;NID1;LAMC3

NID2 has several biochemical functions, for example, calcium ion binding, collagen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NID2 itself. We selected most functions NID2 had, and list some proteins which have the same functions with NID2. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingTPM4;CD248A;SYT3;PLA2G5;SNCB;AMY2A;EPDL1;PCDH2G1;PCDH2AA3
collagen bindingPCOLCE2;MRC2;PODN;CTSS;PAK1;LACRT;ADAM9;NID1;PCOLCE
protein bindingPAK6;PTPRZ1;SPAST;ATP5A1;EDNRA;PLK1S1;ZFYVE27;OLA1;KIF6

NID2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NID2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NID2.

SKIL; q9wmx2-pro_0000037548

Britze, A; Birkler, RID; et al. Large-Scale Proteomics Differentiates Cholesteatoma from Surrounding Tissues and Identifies Novel Proteins Related to the Pathogenesis. PLOS ONE 9:-(2014).
Maldonado, L; Brait, M; et al. An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine. ONCOTARGET 5:5218-5233(2014).
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