NIT2
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Official Full Name
nitrilase family, member 2
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Overview
Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle. -
Synonyms
NIT2; nitrilase family, member 2; omega-amidase NIT2; Nit protein 2; nitrilase homolog 2; MGC111199;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Arabidopsis thaliana
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Tag Free
- Involved Pathway
- Protein Function
- Interacting Protein
NIT2 involved in several pathways and played different roles in them. We selected most pathways NIT2 participated on our site, such as Alanine, aspartate and glutamate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NIT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alanine, aspartate and glutamate metabolism | AGXT2;GFPT1;GAD1;GLS2;GLSA;DDO;ASPA;NAT8L;GLULA |
NIT2 has several biochemical functions, for example, omega-amidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NIT2 itself. We selected most functions NIT2 had, and list some proteins which have the same functions with NIT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| omega-amidase activity |
NIT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NIT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NIT2.
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