nlrp11
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  • Official Full Name
  • NLR family, pyrin domain containing 11
  • Background
  • NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs,;such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a;NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636),;also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD).;NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in;multiprotein complexes called inflammasomes (Tschopp et al., 2003 (PubMed 12563287)).
  • Synonyms
  • NLRP11; NLR family, pyrin domain containing 11; NACHT, leucine rich repeat and PYD containing 11 , NALP11; NACHT, LRR and PYD domains-containing protein 11; CLR19.6; NOD17; nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 11; PAN10; PYPAF6; FLJ26273; NACHT leucine rich repeat and PYD containing 11; NACHT LRR and PYD domains containing protein 11; NAL11_HUMAN; NALP11; NLR family pyrin domain containing 11; Nucleotide binding oligomerization domain protein 17; Nucleotide-binding oligomerization domain protein 17; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 11; PAAD and NACHT containing protein 10B; PAAD and NACHT domain containing protein 10; PAAD-and NACHT domain-containing protein 10; PYPAF7; PYRIN containing APAF1 like protein 6; PYRIN-containing APAF1-like protein 6; PAAD- and NACHT-containing protein 10; PAAD- and NACHT-containing protein 10B; NACHT, LRR and PYD containing protein 11; NACHT, leucine rich repeat and PYD containing 11
Cat.#:NLRP11-5919HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NLRP11 Protein, GST-tagged
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Cat.#:NLRP11-3045RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NLRP11 Protein, His-tagged
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Cat.#:NLRP11-3802HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NLRP11 293 Cell Lysate
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Protein Function

NLRP11 has several biochemical functions, for example, ATP binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NLRP11 itself. We selected most functions NLRP11 had, and list some proteins which have the same functions with NLRP11. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CASK; PTK2AB; MTPAP; PRKCE; MYO1H; TTLL12; PRKD3; TK2; DDX4; ARAF
Function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
Related Protein MOXD1; NLRP11; MOXD1L; MOXD2
Function poly(A) RNA binding
Related Protein RALYL; NGRN; ERH; LSM14A; NOM1; MOV10; SUPT6H; DDX23; RPSA; RPL12

NLRP11 Related Articles

Akhter, A; Caution, K; et al. Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization. IMMUNITY 37:35-47(2012).
Beardsley, AJ; Li, Y; et al. Characterization of a diverse secretome generated by the mouse preimplantation embryo in vitro. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 8:-(2010).