nlrp2
Share
  • Official Full Name
  • NLR family, pyrin domain containing 2
  • Background
  • NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in;the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be;involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 (PubMed;12563287)).
  • Synonyms
  • NLRP2; NLR family, pyrin domain containing 2; NACHT, leucine rich repeat and PYD containing 2 , NALP2; NACHT, LRR and PYD domains-containing protein 2; CLR19.9; FLJ20510; NBS1; nucleotide binding oligomerization domain; leucine rich repeat and pyrin domai
Cat.#:NLRP2-5921HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NLRP2 Protein, GST-tagged
+Inquiry
Cat.#:NLRP2-3046RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NLRP2 Protein, His-tagged
+Inquiry
Cat.#:NLRP2-3800HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NLRP2 293 Cell Lysate
+Inquiry

Involved Pathway

NLRP2 involved in several pathways and played different roles in them. We selected most pathways NLRP2 participated on our site, such as NOD pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NLRP2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
NOD pathway
NLRP12; AAMP; COPS6; NLRP2; NLRP7; SUGT1; NLRP10; PRDM1; NLRP3; NLRP4

Protein Function

NLRP2 has several biochemical functions, for example, ATP binding, Pyrin domain binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NLRP2 itself. We selected most functions NLRP2 had, and list some proteins which have the same functions with NLRP2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PAK2B; OBSCN; NARS2; ACVR1; NTRK3; DYRK4; NMRK2; UBE2D1B; DHX32A; KIF18B
Function Pyrin domain binding
Related Protein CASPA; NLRP2; PYCARD
Function protein binding
Related Protein BARHL2; PSTPIP1; EMILIN1; AOC3; RAI1; NTHL1; FNBP4; MST1; CHD2; PRR3

Interacting Protein

NLRP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLRP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLRP2.
PYDC2; H2AFX; WRN; RBBP6; BECN1; TPP1; NLRP5; TTF1; TAF13; BCL7B; CRIPT