NQO2
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Official Full Name
NAD(P)H dehydrogenase, quinone 2
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Overview
NQO2 (EC 1.10.99.2) is a flavoprotein that catalyzes the 2-electron reduction of various quinones, redox dyes, and the;vitamin K menadione. NQO2 predominantly uses dihydronicotinamide riboside (NRH) as the electron donor (summary by Wu;et al., 1997 (PubMed 9367528)). -
Synonyms
NQO2; NAD(P)H dehydrogenase, quinone 2; NAD(P)H menadione oxidoreductase 2, dioxin inducible , NMOR2; ribosyldihydronicotinamide dehydrogenase [quinone]; DHQV; DIA6; QR2; Ox2; EC 1.10.99.2; MGC94180; NAD(P)H dehydrogenase quinone 2; NAD(P)H menadione oxidoreductase 1 dioxin inducible 2; NAD(P)H menadione oxidoreductase 2 dioxin inducible; NMOR2; NQO 2; NRH dehydrogenase; NRH:quinone oxidoreductase 2; OTTHUMP00000015948; OTTHUMP00000015949; OTTHUMP00000015953; Ox 2; Quinone; Quinone reductase 2; Ribosyldihydronicotinamide dehydrogenase; OTTHUMP00000015950; OTTHUMP00000015951; OTTHUMP00000015952; NRH dehydrogenase [quinone] 2; NAD(P)H menadione oxidoreductase 2, dioxin-inducible; NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- Yeast
- GST
- His
- His (Fc)
- Avi
- His|SUMO
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
NQO2 involved in several pathways and played different roles in them. We selected most pathways NQO2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NQO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
NQO2 has several biochemical functions, for example, NADPH dehydrogenase (quinone) activity, electron carrier activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NQO2 itself. We selected most functions NQO2 had, and list some proteins which have the same functions with NQO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NADPH dehydrogenase (quinone) activity | NQO2;CBR4 |
| electron carrier activity | NCF2;AKR1B1;ACOX3;ACOX2;ME2;UGDH;SDHD;ACAD11;GRX2 |
| metal ion binding | CYP1C1;HELZ2;Car12;ZBTB48;CYP2AD2;CYP11C1;ZDHHC16A;ZFY1;ZFP687 |
| protein binding | IPO5;EDC4;Car4;SCGB2A2;APOA1BP;CCDC93;NACA;TAF6L;TUB |
NQO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NQO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NQO2.
LRRC7; imatinib; RELB; RHOB; prlC; groL; ytfE; GORASP2; bosutinib; dasatinib; midostaurin; sch51344; Smad6; EGFR
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