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NRL

Official Full Name

neural retina leucine zipper
Overview

This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases.
Synonyms

NRL; neural retina leucine zipper; neural retina-specific leucine zipper protein; D14S46E; NRL MAF; RP27; Neural retinal specific leucine zipper; NRL_HUMAN; neural retinal-specific leucine zipper; NRL-MAF;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
His|SUMO|Myc
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NRL-1368H	Recombinant Human NRL, GST-tagged	E.coli	GST	1-237aa	$319 / 25ug
Human	NRL-293H	Recombinant Human NRL	Mammalian Cell	His		Inquiry
Human	NRL-749H	Recombinant Human NRL Protein, His-tagged	E.coli	His		Inquiry
Human	NRL-3693HCL	Recombinant Human NRL 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NRL-3293H	Recombinant Human NRL protein, His&Myc-tagged	E.coli	His&Myc	1-237aa	Inquiry
Human	NRL-3683H-B	Recombinant Human NRL Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	NRL-3683H	Recombinant Human NRL Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	NRL-10894M	Recombinant Mouse NRL Protein	Mammalian Cell	His		Inquiry
Mouse	NRL-2535M	Recombinant Mouse NRL Protein (1-237 aa), His-SUMO-Myc-tagged	E.coli	His/SUMO/Myc	1-237 aa	Inquiry
Mouse	NRL-6206M	Recombinant Mouse NRL Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	NRL-6206M-B	Recombinant Mouse NRL Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	NRL-3762Z	Recombinant Zebrafish NRL	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
NRL Related Articles

NRL involved in several pathways and played different roles in them. We selected most pathways NRL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NRL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NRL has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, leucine zipper domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRL itself. We selected most functions NRL had, and list some proteins which have the same functions with NRL. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	NKX3.3;ZNF556;ZKSCAN5;HIC2;PAX3A;Ar;IRF2;ZFP39;LIG1
RNA polymerase II core promoter proximal region sequence-specific DNA binding	NKX3-2;CREB3;MAFB;POU1F1;CHD7;ZNF695;CDX4;NR3C1;ZBTB7A
leucine zipper domain binding	DAPK3;ATF4;AATF;MKL1;CRX;PMF1;NRL;PAWR;KCNA3
protein binding	HLA-DOA;CHST13;SIX3;TRAPPC2L;DPCD;MED15;ZKSCAN1;MAP2K2;PIK3C3
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	SMAD2;CTCFL;BARHL2;STAT3;TP63;RUNX2;GLIS2;HOXA10;NEUROD1

NRL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRL here. Most of them are supplied by our site. Hope this information will be useful for your research of NRL.

CRX; Rax

Wang, CX; Hosono, K; et al. Interaction between optineurin and the bZIP transcription factor NRL. CELL BIOLOGY INTERNATIONAL 38:16-25(2014).

von der Gathen, Y; Sander, I; et al. Quantification of protein and latex allergen content of various natural rubber latex products. ALLERGOLOGIE 35:310-322(2012).