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Nsf

  • Official Full Name

    N-ethylmaleimide-sensitive factor

  • Overview

    Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
  • Synonyms

    NSF; N-ethylmaleimide-sensitive factor; vesicle-fusing ATPase; N ethylmaleimide sensitive factor like protein; SKD2; NEM-sensitive fusion protein; vesicular-fusion protein NSF; N-ethylmaleimide-sensitive fusion protein; N-ethylmaleimide-sensitive factor-l;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NSF-7980H Recombinant Human NSF protein, His & T7-tagged E.coli His/T7 Asp590~Asp744 (Accession # P46459)
Human NSF-1372H Recombinant Human NSF protein(394-744 aa), His-tagged E.coli N-His 394-744 aa
Human NSF-3688HCL Recombinant Human NSF 293 Cell Lysate HEK293 N/A
Human NSF-1227HFL Recombinant Full Length Human NSF Protein, C-Flag-tagged Mammalian cells Flag
Human NSF-1549H Recombinant Human NSF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NSF-4739H Recombinant Human NSF Protein (Asp590-Asp744), N-His tagged E.coli N-His Asp590-Asp744
Human NSF-1549H-B Recombinant Human NSF Protein Pre-coupled Magnetic Beads HEK293
Mouse NSF-10909M Recombinant Mouse NSF Protein Mammalian Cell His
Mouse Nsf-4506M Recombinant Mouse Nsf Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NSF-6218M Recombinant Mouse NSF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NSF-6218M-B Recombinant Mouse NSF Protein Pre-coupled Magnetic Beads HEK293
Rat NSF-4091R Recombinant Rat NSF Protein Mammalian Cell His
Rat NSF-3752R-B Recombinant Rat NSF Protein Pre-coupled Magnetic Beads HEK293
Rat NSF-3752R Recombinant Rat NSF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NSF-1282R Recombinant Rat NSF Protein (7-209 aa), His-tagged E.coli His 7-209 aa
Chicken NSF-2180C Recombinant Chicken NSF Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Nsf Related Articles

Nsf involved in several pathways and played different roles in them. We selected most pathways Nsf participated on our site, such as Synaptic vesicle cycle, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Nsf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Synaptic vesicle cycleATP6V1H;SYT1;CPLX2;UNC13A;ATP6V0E;ATP6V0A4;NSF;ATP6V0D1;ATP6V1E1
GABAergic synapseSLC38A2;GABRA1;GABRD;GNG10;GAD1;PRKCG;GNG7;GABRG1;GNG13

Nsf has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled. Some of the functions are cooperated with other proteins, some of the functions could acted by Nsf itself. We selected most functions Nsf had, and list some proteins which have the same functions with Nsf. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSLFN5;MB21D1;MYLK3;ACTA1;GLUD1;PRKY;VRK3;RNASEL;GATB
ATPase activityOLA1;ABCC5;PSMC3;ABCB1A;KIF4A;ABCA9;ABCD1;IDE;DYNC2H1
ATPase activity, coupledHSP104;HSPA1B;ABCB1A;NSF;PEX1;VPS4A;MYH3;HSPA1A;CCT8
PDZ domain bindingSLC9A3;GRIA1;GRIK2;LPAR2;Fzd4;PTEN;PDZK1;GRASP;ARHGEF16
Rab GTPase bindingSYTL3;MYO5B;LLGL2;ACAP2;STX4A;LLGL1;RAB11FIP2;MYRIP;RABGGTA
metal ion bindingDSG1C;CNOT6L;CHEK2;CTDSP1;ZC3H3;ESYT1;GM3258;SMYD2B;ZNF701
protein bindingINO80;PEX11B;GTF2H4;KIAA0947;CAMK2A;GTF3C6;TUBGCP4;SPDYE2;LRRC29
protein complex bindingCDKN1A;TXN2;UQCRFS1;COG2;FADD;STRN;CFLAR;PPARA;SLC25A3
protein kinase bindingMSH2;CSPG4;IKBKB;CD36;TRIM6;VDAC1;RHEB;FAM83D;TRAF3
syntaxin-1 bindingSNAP25A;GOLSYN;SNAP25B;SYT1;CPLX1;SYBU;STXBP2;RNF40;NSF

Nsf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Nsf here. Most of them are supplied by our site. Hope this information will be useful for your research of Nsf.

GABBR2; NAPA; GABBR1; GRIA2; PTPN9; FES; PTPRC; FER; PTPRB; PTPRG; PTPN12; PTPRJ

Ramakrishnan, NA; Drescher, MJ; et al. Calcium Regulates Molecular Interactions of Otoferlin with Soluble NSF Attachment Protein Receptor ( SNARE) Proteins Required for Hair Cell Exocytosis*. JOURNAL OF BIOLOGICAL CHEMISTRY 289:8750-8766(2014).
Rout, M; Senapati, MR; et al. Serosurveillance of foot-and-mouth disease in sheep and goat population of India. PREVENTIVE VETERINARY MEDICINE 113:273-277(2014).
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