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NUDT15

  • Official Full Name

    nudix (nucleoside diphosphate linked moiety X)-type motif 15

  • Synonyms

    NUDT15;nudix (nucleoside diphosphate linked moiety X)-type motif 15;23063;ENSG00000136159;MTH2;RP11-90M2.1;13q14.2;FLJ10956, MGC104352;probable 8-oxo-dGTP diphosphatase NUDT15;probable 8-oxo-dGTP diphosphatase NUDT15;A730068G11Rik;mutT homolog 2;nudix motif 15;nudix-type motif 15;8-oxo-dGTPase NUDT15;7,8-dihydro-8-oxoguanine-triphosphatase NUDT15;nucleoside diphosphate-linked moiety X motif 15;probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15;EC 3.6.1.55;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Nicotiana Benthamiana
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NUDT15-133H Recombinant Human NUDT15 Protein, His-tagged E.coli His 2-164
Human NUDT15-3651HCL Recombinant Human NUDT15 293 Cell Lysate HEK293 N/A
Human NUDT15-11H Recombinant Human NUDT15 Protein, His-tagged Nicotiana Benthamiana His
Human NUDT15-4386H Recombinant Human NUDT15 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NUDT15-892HFL Recombinant Full Length Human NUDT15 Protein, C-Flag-tagged Mammalian cells Flag
Human NUDT15-1560H-B Recombinant Human NUDT15 Protein Pre-coupled Magnetic Beads HEK293
Human NUDT15-1560H Recombinant Human NUDT15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NUDT15-10965M Recombinant Mouse NUDT15 Protein Mammalian Cell His
Mouse NUDT15-6250M-B Recombinant Mouse NUDT15 Protein Pre-coupled Magnetic Beads HEK293
Mouse NUDT15-6250M Recombinant Mouse NUDT15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nudt15-4536M Recombinant Mouse Nudt15 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish NUDT15-337Z Recombinant Zebrafish NUDT15 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NUDT15 Related Articles

NUDT15 involved in several pathways and played different roles in them. We selected most pathways NUDT15 participated on our site, such as Metabolism, Metabolism of nucleotides, Phosphate bond hydrolysis by NUDT proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MetabolismTPMT.2;NFYBB;CYP3A7;B3GNT2;CYP2Y3;FA2H;AWAT1;LMF1;VAPB
Metabolism of nucleotidesADA;TM9SF1;ADK;DPYS;PROZA;ADAL;NUDT1;DPYDA.1;NUDT5
Phosphate bond hydrolysis by NUDT proteinsNUDT1;NUDT18;NUDT5;NUDT16;NUDT15

NUDT15 has several biochemical functions, for example, 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity, 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT15 itself. We selected most functions NUDT15 had, and list some proteins which have the same functions with NUDT15. You can find most of the proteins on our site.

Function Related Protein
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activityNUDT15;NUDT1
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activityNUDT1;NUDT15;NUDT19;DOM3Z
metal ion bindingADAP1;SP8A;ZFP41;ZNF193;KLF1;ZFAND5B;CLCA3;KDM3B;OTUD7A

NUDT15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT15 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT15.

SRD5A3

Yang, SK; Hong, M; et al. A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia. NATURE GENETICS 46:1017-+(2014).
Teruya, R; Ikejiri, AT; et al. Expression of oxidative stress and antioxidant defense genes in the kidney of inbred mice after intestinal ischemia and reperfusion. ACTA CIRURGICA BRASILEIRA 28:848-855(2013).
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