nup50
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  • Official Full Name
  • nucleoporin 50kDa
  • Background
  • The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms
  • NUP50; nucleoporin 50kDa; NPAP60; NPAP60L; nuclear pore complex protein Nup50; nucleoporin Nup50; 50 kDa nucleoporin; nuclear pore-associated protein 60L;
Cat.#:NUP50-1418HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUP50, GST-tagged
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Cat.#:NUP50-1504HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUP50 protein, His & T7-tagged
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Cat.#:NUP50-10998MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NUP50 Protein
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Cat.#:Nup50-1505MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Nup50 protein, His & T7-tagged
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Cat.#:Nup50-1506RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Nup50 protein, His & GST-tagged
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Cat.#:NUP50-3139RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NUP50 Protein, His-tagged
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Cat.#:NUP50-1915CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NUP50
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Cat.#:NUP50-11562ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NUP50
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Cat.#:NUP50-3629HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NUP50 293 Cell Lysate
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Involved Pathway

NUP50 involved in several pathways and played different roles in them. We selected most pathways NUP50 participated on our site, such as Antiviral mechanism by IFN-stimulated genes, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Antiviral mechanism by IFN-stimulated genes
MX2; HERC5; IFIT12; IFIT14; KPNA3; DPF1; EIF4G2; EIF4G1; UBE2L6; EIF4E
Cell Cycle
CDC7; SKP2; MCM6; BRCC3; CCND2A; YWHAG; CENPL; CLASP1; NSL1; DBF4
Cell Cycle, Mitotic
KIF20A; H3F3D; GINS4; BORA; NDEL1; DBF4; TCTN2; TMEM188; ITGB3BP; INCENP
Cellular response to heat stress
DPF1; EEF1A1; DNAJB6; HSPA12B; BAG3; ST13; KIAA1967; HSPA14; NUP50; PTGES3
Cellular responses to stress
MAPKAPK2B; TERF2IP; DYNLL2A; HIST1H1A; PHC2; HBXIP; PRDX2; RBBP7; TERF1; DPF1
Cytokine Signaling in Immune system
NUP50; IFI6; IFIT3; TRIM68; CSH1; FGF8B; MX2; TRIM5; JAK1; FGF20A
Disease
STX1B; TIRAP; RCC1; LRRFIP1; FMOD; HDAC6; HEYL; AP2S1; FDXR; KREMEN2
Export of Viral Ribonucleoproteins from Nucleus
NUPL2; NUP35; DPF1; NUP50

Protein Function

NUP50 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP50 itself. We selected most functions NUP50 had, and list some proteins which have the same functions with NUP50. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ELANE; LYRM2; SH3PXD2A; SCOC; SRGN; TREML2; CALML3; NEK11; PCDH18; KIAA1217

Interacting Protein

NUP50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP50 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP50.
KPNA1; KPNA4; KPNA5; KPNA6; KPNA2; KPNA2; KPNA2