naga
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  • Official Full Name
  • N-acetylgalactosaminidase, alpha-
  • Background
  • NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause ofSchindler disease types I and II (type II also known as Kanzaki disease).
  • Synonyms
  • NAGA; N-acetylgalactosaminidase, alpha-; alpha-N-acetylgalactosaminidase; D22S674; Alpha galactosidase B; Acetylgalactosaminidase, alpha N (alpha galactosidase B); Alpha N acetylgalactosaminidase; GALB; N acetylgalactosaminidase, alpha; alpha-galactosidase B; Acetylgalactosaminidase, alpha-N- (alpha-galactosidase B)
Cat.#:NAGA-792HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NAGA Protein, His-tagged
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Cat.#:Naga-794MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Naga Protein, His-tagged
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Cat.#:Naga-796RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Naga Protein, His-tagged
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Cat.#:NAGA-344HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human NAGA, His-tagged
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Cat.#:NAGA-3891RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NAGA Protein
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Cat.#:NAGA-4019CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NAGA
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Cat.#:NAGA-3513ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NAGA
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Cat.#:NAGA-401CTag:Met/His
Source (Host):E. coliSpecies:C.perfringens
Product nameRecombinant C. perfringens NAGA, Met&His-tagged
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Cat.#:NAGA-4138BTag:His
Source (Host):E. coli or YeastSpecies:Bacillus subtilis
Product nameRecombinant Bacillus subtilis NAGA protein, His-tagged
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Cat.#:NAGA-3983HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NAGA 293 Cell Lysate
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Involved Pathway

NAGA involved in several pathways and played different roles in them. We selected most pathways NAGA participated on our site, such as Glycosphingolipid biosynthesis - globo series, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with NAGA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosphingolipid biosynthesis - globo series
B3GALNT1; HEXB; FUT1; A4GALT; B3GALT5; NAGA; FUT9A; HEXA; ST3GAL1; GBGT1L4
Lysosome
SLC11A1; GLA; AP4M1; AP1S2; M6PR; CTNS; GNS; ATP6V0D1; GUSB; PPT1

Protein Function

NAGA has several biochemical functions, for example, alpha-N-acetylgalactosaminidase activity, alpha-galactosidase activity, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NAGA itself. We selected most functions NAGA had, and list some proteins which have the same functions with NAGA. You can find most of the proteins on our site.
Function
Related Protein
Function alpha-N-acetylgalactosaminidase activity
Related Protein NAGA
Function alpha-galactosidase activity
Related Protein NAGA; GLA
Function protein homodimerization activity
Related Protein GPD1L; ASGR1; DARS2; SLC39A13; GM5506; UGT1A1; QDPR; BCL2L10; PAFAH1B1; NCR3

NAGA Related Articles

Qing, YF; Zhang, QB; et al. Changes in toll-like receptor (TLR)4-NF kappa B-IL1 beta signaling in male gout patients might be involved in the pathogenesis of primary gouty arthritis. RHEUMATOLOGY INTERNATIONAL 34:213-220(2014).
Choi, CW; An, HY; et al. Characterization of Streptococcus pneumoniae N-Acetylglucosamine-6-Phosphate Deacetylase as a Novel Diagnostic Marker. JOURNAL OF MICROBIOLOGY 51:659-664(2013).