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NEBL

  • Official Full Name

    nebulette

  • Overview

    This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
  • Synonyms

    NEBL; nebulette; LIM-nebulette; actin-binding Z-disk protein; LASP2; LNEBL; FLJ53769; MGC119746; MGC119747;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NEBL-1246H Recombinant Human NEBL, GST-tagged E.coli GST 201-550aa
Human NEBL-1485H Recombinant Human NEBL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NEBL-590H Recombinant Human NEBL Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NEBL-1820H Recombinant Human NEBL Protein, His&GST-tagged E.coli N-His&GST Met1-Ala264
Mouse NEBL-10552M Recombinant Mouse NEBL Protein Mammalian Cell His
Mouse NEBL-5997M Recombinant Mouse NEBL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nebl-4351M Recombinant Mouse Nebl Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NEBL-5997M-B Recombinant Mouse NEBL Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NEBL-2224Z Recombinant Zebrafish NEBL Mammalian Cell His
Chicken NEBL-6058C Recombinant Chicken NEBL Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NEBL involved in several pathways and played different roles in them. We selected most pathways NEBL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NEBL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

NEBL has several biochemical functions, for example, actin filament binding, cytoskeletal protein binding, filamin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEBL itself. We selected most functions NEBL had, and list some proteins which have the same functions with NEBL. You can find most of the proteins on our site.

Function Related Protein
actin filament bindingAIF1;ANTXR1;PKNOX2;BLOC1S6;TRIOBPB;RCSD1;WIPF3;FSCN1A;CORO1C
cytoskeletal protein bindingSLC8A1;DYNLL2;TPM1;EPB41L5;NF2B;LIN7C;PTPN4;ANXA2A;MYPN
filamin bindingZNF664-FAM101A;FBLIM1;PDLIM2;HSPB7;TMEM67;FAM101B;NEBL;FAM101A;MICALL2
protein bindingNRF1;FANCF;IL23;ADAP1;RCN1;CD84;PIGS;THRAA;BSCL2
structural constituent of musclePDLIM3;TTN;MYL6;MYL3;OBSCN;ANKRD2;TPM1;MYLPF;CSRP3
tropomyosin bindingPYCARD;TMOD2;LMOD3;TNNT1;TMOD1;TMOD3;TNNT3;NEBL;LMOD2A

NEBL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEBL here. Most of them are supplied by our site. Hope this information will be useful for your research of NEBL.

b2r8y4_human; HOMER3; TRIM27; GOLGA2; TRAF2; TRAF1; FLJ13057

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