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OCA2

Official Full Name

oculocutaneous albinism II
Overview

This gene encodes the human homologue of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine - a precursor of melanin. Mutations in this gene result in type 2 oculocutaneous albinism.
Synonyms

OCA2; oculocutaneous albinism II; D15S12, EYCL2, EYCL3, eye color 2 (central brown) , eye color 3 (brown) , oculocutaneous albinism II (pink eye dilution (murine) homolog) , oculocutaneous albinism II (pink eye dilution homolog, mouse) , P; P protein; BEY; BEY1; BEY2; EYCL; melanocyte specific transporter protein; BOCA; D15S12; EYCL2; HCL3; PED; EYCL3; eye color 2 (central brown); eye color 3 (brown); hair color 3 (brown); Melanocyte-specific transporter protein; oculocutaneous albinism II (pink-eye dilution homolog, mouse); P; P_HUMAN; Pink eyed dilution protein homolog; Pink-eyed dilution protein homolog; SHEP1; total brown iris pigmentation;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	OCA2-30532TH	Recombinant Human OCA2	Wheat Germ	N/A	100 amino acids	Inquiry
Human	OCA2-2919H	Recombinant Human OCA2 protein, His-tagged	E.coli	His	1-174 aa	$319 / 25ug
Mouse	OCA2-11062M	Recombinant Mouse OCA2 Protein	Mammalian Cell	His		Inquiry
Mouse	OCA2-6306M	Recombinant Mouse OCA2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	OCA2-6306M-B	Recombinant Mouse OCA2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

OCA2 involved in several pathways and played different roles in them. We selected most pathways OCA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OCA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

OCA2 has several biochemical functions, for example, L-tyrosine transmembrane transporter activity, protein binding, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OCA2 itself. We selected most functions OCA2 had, and list some proteins which have the same functions with OCA2. You can find most of the proteins on our site.

Function	Related Protein
L-tyrosine transmembrane transporter activity
protein binding	EGFR;KLF5;CEP152;PTH1R;AP3S1;ZFAND2B;ZNF223;ZMAT4;SARM1
transporter activity	CDH17;SV2C;SLC17A9B;FXYD2;TAP2;HIATL2;TTPA;SLC2A8;SLC22A13

OCA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OCA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OCA2.

ATP13A2