OCLN
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Official Full Name
occludin
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Overview
This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. -
Synonyms
OCLN; occludin; tight junction protein occludin TM4 minus; tight junction protein occludin; BLCPMG; FLJ08163; FLJ18079; FLJ77961; FLJ94056; MGC34277;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Canis lupus familiaris (Dog) (Canis familiaris)
- Chicken
- Gallus gallus (Chicken)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Potorous tridactylus (Potoroo)
- Rat
- Rattus norvegicus (Rat)
- Xenopus laevis (African clawed frog)
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | OCLN-27766TH | Recombinant Human OCLN | Wheat Germ | N/A | 522 amino acids |
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| Human | OCLN-1440H | Recombinant Human OCLN, GST-tagged | E.coli | GST | 269-522aa | |
| Human | OCLN-27768TH | Recombinant Human OCLN | Wheat Germ | N/A | 100 amino acids |
|
| Human | OCLN-3603H | Recombinant Human OCLN protein, MYC/DDK-tagged | HEK293 | Myc/DDK |
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| Human | OCLN-3603HCL | Recombinant Human OCLN 293 Cell Lysate | HEK293 | N/A |
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| Human | OCLN-9487HFL | Recombinant Full Length Human OCLN protein, Flag-tagged | Mamanlian cells | Flag |
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| Human | OCLN-352HF | Recombinant Full Length Human OCLN Protein | In Vitro Cell Free System | 522 amino acids |
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| Human | OCLN-2523H | Recombinant Human OCLN Protein, His-tagged | E.coli | N-His | Lys266-Thr522 |
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| Human | OCLN-3859H | Recombinant Human OCLN Protein (Lys266-Thr522), His tagged | E.coli | His | Lys266-Thr522 |
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| Mouse | Ocln-425M | Recombinant Mouse Ocln Protein, His-tagged | E.coli | His | Phe17~Ser107 |
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| Mouse | Ocln-4569M | Recombinant Mouse Ocln Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | Ocln-1882M | Recombinant Mouse Ocln Protein, His-tagged | E.coli | N-His | Lys264-Pro521 |
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| Rat | OCLN-4153R | Recombinant Rat OCLN Protein | Mammalian Cell | His |
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| Rat | OCLN-3815R | Recombinant Rat OCLN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | OCLN-3815R-B | Recombinant Rat OCLN Protein Pre-coupled Magnetic Beads | HEK293 |
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| Canis lupus familiaris (Dog) (Canis familiaris) | RFL15045CF | Recombinant Full Length Dog Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-521) |
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| Gallus gallus (Chicken) | RFL27577GF | Recombinant Full Length Chicken Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-504) |
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| Homo sapiens (Human) | RFL33863HF | Recombinant Full Length Human Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-522) |
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| Mus musculus (Mouse) | RFL15777MF | Recombinant Full Length Mouse Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-521) |
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| Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL6522PF | Recombinant Full Length Pongo Abelii Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-522) |
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| Potorous tridactylus (Potoroo) | RFL35773PF | Recombinant Full Length Potorous Tridactylus Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-489) |
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| Rattus norvegicus (Rat) | RFL2330RF | Recombinant Full Length Rat Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-523) |
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| Xenopus laevis (African clawed frog) | RFL1932XF | Recombinant Full Length Xenopus Laevis Occludin(Ocln) Protein, His-Tagged | E.coli expression system | His | Full Length (1-493) |
|
| Chicken | OCLN-6685C | Recombinant Chicken OCLN | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- OCLN Related Articles
- OCLN Related Research Area
OCLN involved in several pathways and played different roles in them. We selected most pathways OCLN participated on our site, such as Apoptosis, Apoptotic cleavage of cell adhesion proteins, Apoptotic cleavage of cellular proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with OCLN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Apoptosis | TNFSF10;PIK3CD;IL1A;DNM1L;CSF2RB;CRADD;PKP1;CASP2;DERL3 |
| Apoptotic cleavage of cell adhesion proteins | CTNNB1;PKP1;PTBP3;OCLN;DSG3;DSG2;CTNNB2;DSG1;DSP |
| Apoptotic cleavage of cellular proteins | BCAP31;STK24;PLEC;CASP8L1;DBNL;DSG1;PTBP3;DSG2;DSG3 |
| Apoptotic execution phase | DSG1;SATB1;GAS2;PLECA;STK24B;LMNB1;STK26;PANK1A;CASP6L1 |
| Cell adhesion molecules (CAMs) | CLDN1;JAM3;SDC4;HLA-DRA;PVRL3B;CLDN15LB;LRRC4C;Itgam&Itgb2;CLDNG |
| Hepatitis C | IFNA4;IFNA8;PIK3R3;CLDN15;NFKB1;PPP2CA;IFN-a;RAF1;TRAF6 |
| Leukocyte transendothelial migration | CLDN15;CLDN20;CLDN11;PXN;RAC1;CLDN5;EZR;ITGAL;PRKCB |
| Pathogenic Escherichia coli infection | WASL;ITGB1;PRKCA;YWHAZ;TUBA1C;TUBA1B;TUBB2B;EZR;TUBA1A |
OCLN has several biochemical functions, for example, protein binding, protein domain specific binding, thiopurine S-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OCLN itself. We selected most functions OCLN had, and list some proteins which have the same functions with OCLN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BOLA1;UFC1;GPKOW;MAP3K8;C1orf50;CAPRIN2;AES;TNFRSF10B;RAB11B |
| protein domain specific binding | PPP3R1;DYNLL1;TRP63;NEDD4;SFN;STXBP1;CTBP1;DDC;LAMP1 |
| thiopurine S-methyltransferase activity | TPMT.2;OCLN;TPMT.1;TPMT |
OCLN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OCLN here. Most of them are supplied by our site. Hope this information will be useful for your research of OCLN.
CSNK1E; SYNE4; CLEC7A; PLSCR1; CSNK1A1; TJP1; ULK1; SNW1
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