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OLR1

  • Official Full Name

    oxidized low density lipoprotein (lectin-like) receptor 1

  • Overview

    This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimers disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
  • Synonyms

    OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; LOX1; LOXIN; SLOX1; CLEC8A; SCARE1; oxidized low-density lipoprotein receptor 1; hLOX-1; ox LDL receptor 1; lectin-type oxidized LDL receptor 1; scavenger receptor class E, member 1; C-type lectin domain family 8 member A; oxidized low-density lipoprotein receptor 1, soluble form;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Cattle
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rabbit
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human
  • Human Cell
  • Insect cells
  • Mammalian Cell
  • Mammalian cells
  • NS0
  • C
  • His
  • Fc|His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human OLR1-2451H Recombinant Human Oxidized Low Density Lipoprotein (Lectin-like) Receptor 1 E.coli N/A
Human OLR1-6997H Recombinant Human OLR1 protein(Ser61-Gln273), His-tagged HEK293 N-His Ser61-Gln273
Human OLR1-1885H Recombinant Human OLR1 protein, His & T7-tagged E.coli His/T7 Leu81~Gln273 (Accession # P78380)
Human OLR1-3631H Recombinant Human OLR1 Human N/A
Human OLR1-1716HCL Recombinant Human OLR1 cell lysate Human Cell N/A
Human OLR1-296H Recombinant Human OLR1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human OLR1-061H Recombinant Human OLR1 protein, His-Avi-tagged HEK293 His-Avi It contains Arg25-Met233 .
Human OLR1-693HFL Active Recombinant Full Length Human OLR1 Protein, C-Flag-tagged Mammalian cells Flag
Human OLR1-4766H Recombinant Human OLR1 Protein (Ser61-Gln273), C-His tagged Mammalian cells C-His Ser61-Gln273
Human OLR1-01H Recombinant Human OLR1 Protein, His-tagged Insect cells His
Human OLR1-5099H Recombinant Human OLR1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human OLR1-1579H Recombinant Human OLR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human OLR1-3306H Recombinant Human OLR1 protein, His-tagged E.coli His 58-273aa
Human OLR1-4768H Recombinant Human OLR1 Protein (Leu81-Gln273), N-His tagged E.coli N-His Leu81-Gln273
Human OLR1-20H Recombinant Human OLR1 protein, GST-tagged E.coli GST 1-273 aa
Human OLR1-1579H-B Recombinant Human OLR1 Protein Pre-coupled Magnetic Beads HEK293
Human OLR1-2808H Recombinant Human OLR1 protein(61-150 aa), C-His-tagged E. coli C-His 61-150 aa
Mouse Olr1-1886M Recombinant Mouse Olr1 protein, His & T7-tagged E.coli His/T7 Arg60~Pro312 (Accession # Q9EQ09)
Mouse OLR1-12146M Recombinant Mouse OLR1 Protein Mammalian Cell His
Mouse Olr1-01M Active Recombinant Mouse Olr1 Protein, His-tagged NS0 His
Mouse Olr1-358M Recombinant Mouse Olr1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse OLR1-6389M Recombinant Mouse OLR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse OLR1-6389M-B Recombinant Mouse OLR1 Protein Pre-coupled Magnetic Beads HEK293
Rat Olr1-8755R Recombinant Rat Olr1, Fc tagged Human Cell Fc/His
Rat Olr1-559R Recombinant Rat Olr1, His-tagged Human Cell His Leu60-Gln364
Rat OLR1-4170R Recombinant Rat OLR1 protein, His-tagged HEK293 His Leu60-Gln364
Rat Olr1-1887R Recombinant Rat Olr1 protein, His & T7-tagged E.coli His/T7 Thr51~Ser314 (Accession # O70156)
Rat OLR1-001RCL Recombinant Rat OLR1 cell lysate Human Cell N/A
Rat OLR1-3832R Recombinant Rat OLR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat OLR1-3832R-B Recombinant Rat OLR1 Protein Pre-coupled Magnetic Beads HEK293
Rabbit OLR1-1888R Recombinant Rabbit OLR1 protein, His & T7-tagged E.coli His/T7 Met55~Glu274 (Accession # Q9XTA8)
Bos taurus (Bovine) RFL34915BF Recombinant Full Length Bovine Oxidized Low-Density Lipoprotein Receptor 1(Olr1) Protein, His-Tagged E.coli expression system His Full Length (1-270)
Cattle OLR1-1884C Recombinant Cattle OLR1 protein, His & T7-tagged E.coli His/T7 Ser57~Gln270 (Accession # P79391)
Cynomolgus Monkey OLR1-8842C Recombinant Cynomolgus OLR1, His tagged Human Cell His
Cynomolgus Monkey OLR1-1170CCL Recombinant Cynomolgus OLR1 cell lysate Human Cell N/A
Homo sapiens (Human) RFL27553HF Recombinant Full Length Human Oxidized Low-Density Lipoprotein Receptor 1(Olr1) Protein, His-Tagged E.coli expression system His Full Length (1-273)
Rattus norvegicus (Rat) RFL17489RF Recombinant Full Length Rat Oxidized Low-Density Lipoprotein Receptor 1(Olr1) Protein, His-Tagged E.coli expression system His Full Length (1-364)
Rhesus Macaque OLR1-3166R Recombinant Rhesus monkey OLR1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque OLR1-2984R Recombinant Rhesus Macaque OLR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque OLR1-2984R-B Recombinant Rhesus Macaque OLR1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

OLR1 involved in several pathways and played different roles in them. We selected most pathways OLR1 participated on our site, such as PPAR signaling pathway, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with OLR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PPAR signaling pathwayScd2;OLR1;PLTP;ACADM;ACADL;DBI;FABP7;ACSL1;CYP27A1
PhagosomeC1RA;FCAR;OLR1;ATP6V1A;ITGA2;FCGR2A;ITGB1;ATP6V0B;ATP6V1H

OLR1 has several biochemical functions, for example, carbohydrate binding, low-density lipoprotein receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OLR1 itself. We selected most functions OLR1 had, and list some proteins which have the same functions with OLR1. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingKLRK1;KLRC2;ASGR2;CD209C;CHI3L2;MAN2A1;REG3G;LGALS2B;FCN3
low-density lipoprotein receptor activityLRP12;LDLR;OLR1;VLDLR;LRP6;CXCL16
protein bindingDCP1B;DYRK1B;ORAI2;PDLIM5;ADCYAP1;CD19;PKD1;PKP1;LRRC33

OLR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OLR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OLR1.

TCP1; CCT4; HSPA1L; CCT6A; CCT3; CCT7; q9bu08_human; M6PR; EEA1

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