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ONECUT1

Official Full Name

one cut homeobox 1
Overview

The protein encoded by HNF6 is Transcriptional activator. Binds the consensus sequence 5-DHWATTGAYTWWD-3 on a varietyof gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.
Synonyms

ONECUT1; one cut homeobox 1; HNF6, HNF6A, one cut domain, family member 1; hepatocyte nuclear factor 6; HNF 6; one cut domain family member 1; one cut domain, family member 1; hepatocyte nuclear factor 6, alpha; HNF6; HNF-6; HNF6A;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ONECUT1-1458H	Recombinant Human ONECUT1, GST-tagged	E.coli	GST	167-292aa	$319 / 25ug
Human	ONECUT1-29373TH	Recombinant Human ONECUT1	E.coli	N/A	465 amino acids	Inquiry
Human	ONECUT1-128H	Recombinant Human ONECUT1	E.coli	N/A		Inquiry
Human	ONECUT1-3576HCL	Recombinant Human ONECUT1 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	ONECUT1-12153M	Recombinant Mouse ONECUT1 Protein	Mammalian Cell	His		Inquiry
Mouse	ONECUT1-6391M-B	Recombinant Mouse ONECUT1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ONECUT1-6391M	Recombinant Mouse ONECUT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	ONECUT1-4186R	Recombinant Rat ONECUT1 Protein	Mammalian Cell	His		Inquiry
Rat	ONECUT1-3848R-B	Recombinant Rat ONECUT1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ONECUT1-3848R	Recombinant Rat ONECUT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	ONECUT1-10852Z	Recombinant Zebrafish ONECUT1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ONECUT1 Related Research Area

ONECUT1 involved in several pathways and played different roles in them. We selected most pathways ONECUT1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with ONECUT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Signaling pathways regulating pluripotency of stem cells	ISL1;FGF2;MAPK12;ACVR1B;PCGF5;Fzd4;WNT8B;HAND1;POU5F1
Maturity onset diabetes of the young	FOXA3;NEUROG3;PKLR;HNF1A;NKX6-1;HES1;SLC2A2;INS2;HNF4G

ONECUT1 has several biochemical functions, for example, DNA binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ONECUT1 itself. We selected most functions ONECUT1 had, and list some proteins which have the same functions with ONECUT1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	TOX4;ZNF530;HMGB4;HOXA4;ZFP473;CHRAC1;TRIM28;SCRT2;SPI1A
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	MITF;MYOG;SMAD1;PAX8;IRF1;DLX3;MEF2B;ISL1;SFPI1

ONECUT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ONECUT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ONECUT1.

Cancer Stem Cell Transcription Factors