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ORC3L

Official Full Name

ORC3 origin recognition complex, subunit 3
Overview

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Synonyms

LAT; ORC3L; LATHEO; origin recognition complex subunit 3; OTTHUMP00000016835; OTTHUMP00000183452; homolog of latheo, Drosophila; origin recognition complex subunit Latheo; origin recognition complex, subunit 3-like; origin recognition complex, subunit 3 honolog;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ORC3L-1259HCL	Recombinant Human ORC3L cell lysate		N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein

ORC3L involved in several pathways and played different roles in them. We selected most pathways ORC3L participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with ORC3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell cycle	CEP164;SUN1;CDC25B;GADD45G;CEP76;SET;RBBP7;DYNC1I2;TMPO

ORC3L has several biochemical functions, for example, DNA replication origin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ORC3L itself. We selected most functions ORC3L had, and list some proteins which have the same functions with ORC3L. You can find most of the proteins on our site.

Function	Related Protein
DNA replication origin binding	HSPD1;CDC45;MCM10;ORC3L;ORC4L;ORC2L;MCM5;ORC4;MCM2
protein binding	CEACAM21;PLEKHG4;ETV4;SAP30BP;BMP2;STAM;POU3F3;NLRC5;CCNK

ORC3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ORC3L here. Most of them are supplied by our site. Hope this information will be useful for your research of ORC3L.

ORC1; ORC6; ORC5