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P2RY11

Official Full Name

purinergic receptor P2Y, G-protein coupled, 11
Overview

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.
Synonyms

P2RY11; purinergic receptor P2Y, G-protein coupled, 11; P2Y purinoceptor 11; P2Y11; P2Y11 receptor; Purinergic receptor P2Y G protein coupled 11; Purinergic receptor P2Y11;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads
Assay Kits

Species

Homo sapiens (Human)
Human
Rhesus Macaque
Zebrafish

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	P2RY11-1496H	Recombinant Human P2RY11, GST-tagged	E.coli	GST	C-110aa	$319 / 25ug
Human	P2RY11-3493HCL	Recombinant Human P2RY11 293 Cell Lysate	HEK293	N/A		Inquiry
Homo sapiens (Human)	RFL10793HF	Recombinant Full Length Human P2Y Purinoceptor 11(P2Ry11) Protein, His-Tagged	E.coli expression system	His	Full Length (1-374)	Inquiry
Rhesus Macaque	P2RY11-3271R	Recombinant Rhesus monkey P2RY11 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	P2RY11-3089R	Recombinant Rhesus Macaque P2RY11 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	P2RY11-3089R-B	Recombinant Rhesus Macaque P2RY11 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	P2RY11-8017Z	Recombinant Zebrafish P2RY11	Mammalian Cell	His		Inquiry
	Kit-0930	TR-FRET PPAR alpha Coactivator Assay Kit, rabbit		N/A		Inquiry
	Kit-1469	P2RY11 CHO-K1 β-Arrestin GPCR Assay Kit		N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein

P2RY11 involved in several pathways and played different roles in them. We selected most pathways P2RY11 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neuroactive ligand-receptor interaction	PTGER1;TAAR14G;AGTR1B;HTR1AA;GABRD;FSHR;GABRG3;NR3C1;HRH1

P2RY11 has several biochemical functions, for example, ATP-activated adenosine receptor activity, G-protein coupled purinergic nucleotide receptor activity, neurotransmitter receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY11 itself. We selected most functions P2RY11 had, and list some proteins which have the same functions with P2RY11. You can find most of the proteins on our site.

Function	Related Protein
ATP-activated adenosine receptor activity	P2RY1;P2RY11
G-protein coupled purinergic nucleotide receptor activity	P2RY14;GPR171;GPR34B;P2RY11;P2RY13;P2RY8;P2RY1;P2RY4;PTAFR
neurotransmitter receptor activity	P2RY11;GRIN3B
receptor activity	ADIPOR1;TACSTD2;ANTXR2B;NLGN4A;NOTCH2;GRIN1A;GRIN2A;CUL5;EXTL3

P2RY11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY11 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY11.

TMED2