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PABPC5

Official Full Name

poly(A) binding protein, cytoplasmic 5
Overview

This gene encodes a protein that binds to the polyA tail found at the 3 end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder.
Synonyms

PABPC5; poly(A) binding protein, cytoplasmic 5; polyadenylate-binding protein 5; PABP5; Poly(A) binding protein 5; Poly(A) binding protein cytoplasmic 5; Polyadenylate binding protein 5;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	PABPC5-3476HCL	Recombinant Human PABPC5 293 Cell Lysate	HEK293	N/A	Inquiry
Human	PABPC5-205H	Recombinant Human PABPC5 Protein, His-tagged	E.coli	His	Inquiry
Rhesus Macaque	PABPC5-3278R	Recombinant Rhesus monkey PABPC5 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	PABPC5-3096R	Recombinant Rhesus Macaque PABPC5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	PABPC5-3096R-B	Recombinant Rhesus Macaque PABPC5 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PABPC5 involved in several pathways and played different roles in them. We selected most pathways PABPC5 participated on our site, such as RNA degradation, RNA transport, mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PABPC5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA degradation	PABPC1B;PAN3;DIS3;PABPC1L;PABPC1A;ENO3;LSM6;CNOT7;TOB2
RNA transport	EIF2B3;TACC3;SRRM1;RPP25;EIF3EB;SMN2;ELAC1;GEMIN6;WIBG
mRNA surveillance pathway	PPP1CBL;PABPC4;DDX39B;CPSF2;CPSF5;PPP2R2B;ETF1A;PPP2R2CA;SMG5

PABPC5 has several biochemical functions, for example, RNA binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PABPC5 itself. We selected most functions PABPC5 had, and list some proteins which have the same functions with PABPC5. You can find most of the proteins on our site.

Function	Related Protein
RNA binding	UPF3A;RPL6;HNRNPAB;KIN;PABPC1L;TNRC6B;IFIT8;RBMS1;PCBP4
nucleotide binding	DIRAS1A;MAPK14B;ORC5;SRSF12;Akap17b;PPIL4;ACTG2;EPHB4B;UCKL1A

PABPC5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PABPC5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PABPC5.

ESR1; ESR2