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PADI1

  • Official Full Name

    peptidyl arginine deiminase, type I

  • Overview

    This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.
  • Synonyms

    PADI1; peptidyl arginine deiminase, type I; protein-arginine deiminase type-1; hPAD colony 10; HPAD10; PAD1; PDI; PDI1; peptidylarginine deiminase type I; protein arginine deiminase type 1; hPAD-colony 10; peptidylarginine deiminase I; protein-arginine de;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PADI1-85H Recombinant Human PADI1, His-tagged E.coli His
Human PADI1-863H Recombinant Human PADI1 Mammalian Cell His
Human PADI1-1605 Recombinant Human PADI1 protein, GST-tagged Insect Cell GST Full Length
Human PADI1-1605H Recombinant Human PADI1, GST-tagged Sf9 Insect Cell GST Full Length
Human PADI1-3471HCL Recombinant Human PADI1 293 Cell Lysate HEK293 N/A
Human PADI1-1727H Recombinant Human PADI1 Protein (1-663 aa), His-tagged Yeast His 1-663 aa
Human PADI1-011H Recombinant Human PADI1 Protein, His-tagged E.coli His 2-663
Human PADI1-118H Recombinant Human PADI1 Protein, His-tagged E. coli His 2-663
Human PADI1-1850HFL Recombinant Full Length Human PADI1 Protein, C-Flag-tagged Mammalian cells Flag
Human PADI1-4943H Recombinant Human PADI1 protein, His-tagged E.coli His 1-663aa
Human PADI1-3781H Recombinant Human PADI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PADI1-3781H-B Recombinant Human PADI1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Padi1-4651M Recombinant Mouse Padi1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PADI1-4248R Recombinant Rat PADI1 Protein Mammalian Cell His
Rat PADI1-3910R Recombinant Rat PADI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PADI1-3910R-B Recombinant Rat PADI1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PADI1 Related Research Area

PADI1 involved in several pathways and played different roles in them. We selected most pathways PADI1 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, protein citrullination, which may be useful for your reference. Also, other proteins which involved in the same pathway with PADI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesHMG20B;BRMS1;VPS72;ATXN7;SETD3;SMARCC1B;NCOA2;SMARCD3B;SMARCB1A
Chromatin organizationCSRP2BP;PAX3A;MBD3A;ATXN7L3;SUZ12;KAT7;PHF8;ELP3;SUDS3
protein citrullinationPADI3;PADI1;PADI2;PADI4;PADI6

PADI1 has several biochemical functions, for example, calcium ion binding, protein-arginine deiminase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PADI1 itself. We selected most functions PADI1 had, and list some proteins which have the same functions with PADI1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingCASQ1;SCUBE3;EPS15L1;S100S;MMP12;PCDHGA10;SYT17;BGLAP-RS1;NOTCH1B
protein-arginine deiminase activityPADI2;PADI6;PADI1;PADI4;PADI3

PADI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PADI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PADI1.

TP53

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