PANK2, pantothenate kinase 2, catalyzes the first step in CoA biosynthesis . Human PANK2 is located in the mitochondria, and some mutations in human PANK2 are linked to neurodegeneration. Alternatively, mouse PANK2 localizes in the cytosol, and defective
PANK2 involved in several pathways and played different roles in them. We selected most pathways PANK2 participated on our site, such as Pantothenate and CoA biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PANK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
PANK2 has several biochemical functions, for example, ATP binding, pantothenate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PANK2 itself. We selected most functions PANK2 had, and list some proteins which have the same functions with PANK2. You can find most of the proteins on our site.
Function ATP binding
Related Protein CCT7; GRK1B; ABCG2A; IPMK; CNTN1B; PTK2B; MARK1; VPS4A; MYHZ1.1; ABCF2A
Function pantothenate kinase activity
Related Protein PANK3; PANK2; PANK4; PANK1B; PANK1
PANK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PANK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PANK2.