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PAPSS1

  • Official Full Name

    3-phosphoadenosine 5-phosphosulfate synthase 1

  • Overview

    Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000
  • Synonyms

    PAPSS1; 3-phosphoadenosine 5-phosphosulfate synthase 1; bifunctional 3-phosphoadenosine 5-phosphosulfate synthase 1; ATPSK1; PAPSS; SK 1; PAPSS 1; PAPS synthase 1; sulfurylase kinase 1; 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1; SK1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PAPSS1-1390H Recombinant Human 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 1, His-tagged E.coli His
Human PAPSS1-1523H Recombinant Human PAPSS1, GST-tagged E.coli GST 1-624aa
Human PAPSS1-471HCL Recombinant Human PAPSS1 lysate HEK293 N/A
Human PAPSS1-5275H Recombinant Human PAPSS1 Protein (Met1-Ala624), C-His tagged Mammalian cells C-His Met1-Ala624
Human PAPSS1-431H Recombinant Human PAPSS1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PAPSS1-2102H Recombinant Human PAPSS1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Papss1-4674M Recombinant Mouse Papss1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish PAPSS1-6986Z Recombinant Zebrafish PAPSS1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PAPSS1 Related Articles

PAPSS1 involved in several pathways and played different roles in them. We selected most pathways PAPSS1 participated on our site, such as Purine metabolism, Selenocompound metabolism, Sulfur metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAPSS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismADSL;GMPR;CANT1A;NUDT9;POLR2D;POLR2EB;POLR3G;AMPD2;ENTPD1
Selenocompound metabolismPAPSS2A;PAPSS2;TXNRD3;SEPHS1;SPS2;MARS;PAPSS2B;TXNRD1;PSTK
Sulfur metabolismPAPSS2A;TST;IMPAD1;cysH;SQRDL;ETHE1;MPST;PAPSS2B;CYCSB
Metabolic pathwaysOAT;OLAH;CYP3A25;ACSS2;CTH;PIGQ;NME4;NDUFB3;CYP11B1

PAPSS1 has several biochemical functions, for example, ATP binding, adenylylsulfate kinase activity, nucleotidyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAPSS1 itself. We selected most functions PAPSS1 had, and list some proteins which have the same functions with PAPSS1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingNPR2;NME3;KIF12;ALPK2;NLRC4;ABCB1A;DHX34;PFTK1;ABCG5
adenylylsulfate kinase activityPAPSS1;PAPSS2;PAPSS2A;PAPSS2B
nucleotidyltransferase activityREV3L;TERT;POLE2;POLR3B;PAPSS2;GMPPAB;POLR2B;GMPPAA;GDPGP1
sulfate adenylyltransferase (ATP) activityPAPSS1;PAPSS2B;PAPSS2;PAPSS2A

PAPSS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAPSS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAPSS1.

Papss1; EEF1A1; UNC119; q81v12_bacan; PPP1R16A; RNASEH2A; NCK1; TMEM132A; Ppp2r1a; Tyw3; FANCI; Rhoa

Mueller, JW; Shafqat, N; et al. Adenosine-5-phosphosulfate - a multifaceted modulator of bifunctional 3-phospho-adenosine-5-phosphosulfate synthases and related enzymes. FEBS JOURNAL 280:3050-3057(2013).
Leung, A; Kwok, B; et al. Silencing of PAPSS1 (3 '-phosphoadenosine 5 '-phosphosulfate synthase 1) potentiates cisplatin activity against non-small cell lung cancer.. CANCER RESEARCH 73:-(2013).
  • Q&As
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