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PARD3

  • Official Full Name

    par-3 partitioning defective 3 homolog (C. elegans)

  • Overview

    This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene.
  • Synonyms

    PARD3; par-3 partitioning defective 3 homolog (C. elegans); par 3 (partitioning defective 3, C.elegans) homolog; partitioning defective 3 homolog; ASIP; atypical PKC isotype specific interacting protein; Baz; Bazooka; PAR3; PARD3A; agouti signaling protein; CTCL tumor antigen se2-5; PAR3 alpha; Partitioning-defective 3 homolog; PARD-3; PAR3-alpha; OTTHUMP00000019427; OTTHUMP00000019428; OTTHUMP00000019429; OTTHUMP00000019430; OTTHUMP00000019431; OTTHUMP00000019432; OTTHUMP00000019434; OTTHUMP00000019435; atypical PKC isotype-specif; SE2-5T2; SE2-5L16; SE2-5LT1; PAR3alpha;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Zebrafish
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PARD3-1283HCL Recombinant Human PARD3 cell lysate N/A
Rat PARD3-4270R Recombinant Rat PARD3 Protein Mammalian Cell His
Rat PARD3-3932R Recombinant Rat PARD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PARD3-3932R-B Recombinant Rat PARD3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PARD3-11753Z Recombinant Zebrafish PARD3 Mammalian Cell His
Chicken PARD3-3343C Recombinant Chicken PARD3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PARD3 involved in several pathways and played different roles in them. We selected most pathways PARD3 participated on our site, such as Rap signaling pathway, Chemokine signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PARD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayFGF5;INS2;PIK3R3;ACTB;LCP2;RAC1;KRIT1;ANGPT1;CALM2
Chemokine signaling pathwayPIK3CB;GNG8;CCR10;RASGRP2;GNGT2;PRKCD;PIK3R3;CXCL3;CXCR4
Neuroactive ligand-receptor interactionCHRNA4B;TAAR12J;P2RY4;HTR1D;CHRNB4;HTR7;RXFP2A;NPY6R;GABRR2
EndocytosisPIP5K1B;IQSEC3;RAB11FIP5;HSPA6;PIP5K1AB;CHMP6;MDM2;PSD2;RAB5AA
Hippo signaling pathwayCTNNA3;CCND2;YAP1;ID1;YWHAZ;BMPR1A;FZD1;BBC3;TCF7L2
Adherens junctionFert2;RAC3A;PVRL2;YES1;TGFBR2;FYN;TCF7L1A;RAC1B;SSX2IP
Tight junctionZAK;MLLT4;TJP1;CTTN;RHOAD;CLDN20;CSNK2A2A;VAPAL;SPTAN1

PARD3 has several biochemical functions, for example, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PARD3 itself. We selected most functions PARD3 had, and list some proteins which have the same functions with PARD3. You can find most of the proteins on our site.

Function Related Protein
phosphatidylinositol-3,4,5-trisphosphate bindingFERMT2;OGT;D6WSU116E;RACGAP1;ARAP3;GAB2;ADAP2;ARAP2;ZFYVE16
phosphatidylinositol-3-phosphate bindingWDR45B;WDR45;D6WSU116E;SNX27;LANCL2;RS1;SNX21;KIF16B;SNX3
phosphatidylinositol-4,5-bisphosphate bindingPLCB1;CHMP3;SYT1;TWF2;KCNJ1;RPH3A;ACTN2;SCIN;CCDC167
protein bindingKIF9;CACNA1SB;PDS5A;KLK13;AKT1;STIM1;TMEM106B;MRPL45;PRDM7
protein kinase C bindingNELL2;YWHAG;PEA15A;HAND2;CASQ2;SDPR;DACT3;ADD3;PRKCB
protein phosphatase bindingIRS2;LCK;CTNNB1;JUP;KCNN4;DRD1;VRK3;ANAPC5;GRB2

PARD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PARD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PARD3.

PARD6A; YWHAB; YWHAZ; Pard6b; YWHAH

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