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PARD6B

  • Official Full Name

    par-6 partitioning defective 6 homolog beta (C. elegans)

  • Overview

    This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.
  • Synonyms

    PARD6B; par-6 partitioning defective 6 homolog beta (C. elegans); par 6 (partitioning defective 6, C.elegans) homolog beta; partitioning defective 6 homolog beta; PAR 6B; PAR 6 beta; Par 6 partitioning defective 6 homolog beta (C. elegans); PAR6B; PARD6 beta; PAR-6 beta; OTTHUMP00000031269;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PARD6B-7058H Recombinant Human PARD6B, His-tagged E.coli His 1-372aa
Human PARD6B-1527H Recombinant Human PARD6B, His-tagged E.coli His 1-372aa
Human PARD6B-3435HCL Recombinant Human PARD6B 293 Cell Lysate HEK293 N/A
Mouse PARD6B-12359M Recombinant Mouse PARD6B Protein Mammalian Cell His
Mouse PARD6B-6496M-B Recombinant Mouse PARD6B Protein Pre-coupled Magnetic Beads HEK293
Mouse PARD6B-6496M Recombinant Mouse PARD6B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PARD6B-5949Z Recombinant Zebrafish PARD6B Mammalian Cell His
Chicken PARD6B-3433C Recombinant Chicken PARD6B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PARD6B Related Articles

PARD6B involved in several pathways and played different roles in them. We selected most pathways PARD6B participated on our site, such as Rap signaling pathway, Endocytosis, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PARD6B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayRAC1;ITGB3;RAPGEF6;FARP2;PIK3R2;NRAS;KITLG;TLN1;RALB
EndocytosisRHOAC;PIP5K1C;RAB11A;HGS;ASAP3;GRK7A;GRK7;IGF2R;ADRB2B
Hippo signaling pathwayWNT3A;FZD5;WTIP;WWTR1;PPP2R2C;SMAD7;DLG1;YWHAZ;PPP1CC
Tight junctionPPP2R1B;PPP2CA;CLDNE;MPDZ;MYH8;MPP5A;GNAIA;CLDN5A;CLDN4

PARD6B has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PARD6B itself. We selected most functions PARD6B had, and list some proteins which have the same functions with PARD6B. You can find most of the proteins on our site.

Function Related Protein
protein bindingCXCR2;ZFPM1;CTLA4;ANKRD1;CASP10;CD8A;SORBS3;SIKE1;RRM1

PARD6B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PARD6B here. Most of them are supplied by our site. Hope this information will be useful for your research of PARD6B.

CDC42; PRKCI

Chen, J; Xu, ZY; et al. Association between DNA methylation and multidrug resistance in human glioma SHG-44 cells. MOLECULAR MEDICINE REPORTS 11:43-52(2015).
Kono, K; Tamashiro, DAA; et al. Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst. DEVELOPMENTAL BIOLOGY 394:142-155(2014).
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