paxip1
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  • Official Full Name
  • PAX interacting (with transcription-activation domain) protein 1
  • Background
  • This gene is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis. [provided by RefSeq, Jul 2008]
  • Synonyms
  • PAXIP1; PAX interacting (with transcription-activation domain) protein 1; PTIP; TNRC2; CAGF28; CAGF29; PACIP1; PAXIP1L; PAX-interacting protein 1; protein encoded by CAG trinucleotide repeats; PAX transcription activation domain interacting protein 1 like;
Cat.#:PAXIP1-12399MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PAXIP1 Protein
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Cat.#:PAXIP1-1463ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PAXIP1
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Cat.#:PAXIP1-3410HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PAXIP1 293 Cell Lysate
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Involved Pathway

PAXIP1 involved in several pathways and played different roles in them. We selected most pathways PAXIP1 participated on our site, such as DNA Double-Strand Break Repair, DNA Repair, Nonhomologous End-Joining (NHEJ), which may be useful for your reference. Also, other proteins which involved in the same pathway with PAXIP1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA Double-Strand Break Repair
CHEK1; CLSPN; CHEK2; UIMC1; BARD1; RAD9; BRE; PAXIP1; TP53BP1; SMARCA5
DNA Repair
ZFP830; TOPBP1; ASCC1; ALKBH3; PARP2; EYA2; ZNF830; KIAA1530; RBBP8; KIAA0146
Nonhomologous End-Joining (NHEJ)
TDP1; TDP2; PAXIP1; TDP2B; RIF1

Protein Function

PAXIP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAXIP1 itself. We selected most functions PAXIP1 had, and list some proteins which have the same functions with PAXIP1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein DNAIC2; CYP2S1; ZBTB7C; BBS5; ZBTB16; CITED1; BEX2; PLIN3; PCNP; KIRREL

Interacting Protein

PAXIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAXIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAXIP1.
TP53BP1; PAGR1; ASH2L; A2M; UMPS; TCN2; SMAD2; ectB; ZBTB8A