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PCDH19

Official Full Name

protocadherin 19
Overview

The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.
Synonyms

PCDH19; protocadherin 19; EFMR, epilepsy, female restricted, with mental retardation (Juberg Hellman syndrome); protocadherin-19; EIEE9; KIAA1313; OTTHUMP00000023649; OTTHUMP00000023650; OTTHUMP00000226658; EFMR;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PCDH19-15H	Recombinant Human PCDH19 protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	PCDH19-12423M	Recombinant Mouse PCDH19 Protein	Mammalian Cell	His		Inquiry
Mouse	PCDH19-6538M	Recombinant Mouse PCDH19 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PCDH19-6538M-B	Recombinant Mouse PCDH19 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	Pcdh19-1906R	Recombinant Rat Pcdh19 Protein, His-tagged	E.coli	N-His	Lys26-Val192	Inquiry
Rhesus Macaque	PCDH19-3320R	Recombinant Rhesus monkey PCDH19 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	PCDH19-3138R	Recombinant Rhesus Macaque PCDH19 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	PCDH19-3138R-B	Recombinant Rhesus Macaque PCDH19 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PCDH19-6801Z	Recombinant Zebrafish PCDH19	Mammalian Cell	His		Inquiry
Chicken	PCDH19-3709C	Recombinant Chicken PCDH19	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PCDH19 Related Articles

PCDH19 involved in several pathways and played different roles in them. We selected most pathways PCDH19 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCDH19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PCDH19 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCDH19 itself. We selected most functions PCDH19 had, and list some proteins which have the same functions with PCDH19. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	OC90;FBN2B;RPH3A;CELSR3;EML1;VSNL1A;S100A13;CBL;S100A9

PCDH19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCDH19 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCDH19.

Ortiz-Medina, H; Emond, MR; et al. ZEBRAFISH CALSYNTENINS MEDIATE HOMOPHILIC ADHESION THROUGH THEIR AMINO-TERMINAL CADHERIN REPEATS. NEUROSCIENCE 286:87-96(2015).

Duszyc, K; Terczynska, I; et al. Epilepsy and mental retardation restricted to females: X-linked epileptic infantile encephalopathy of unusual inheritance. JOURNAL OF APPLIED GENETICS 56:49-56(2015).