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PCDHGC3

  • Official Full Name

    protocadherin gamma subfamily C, 3

  • Overview

    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
  • Synonyms

    PCDHGC3; protocadherin gamma subfamily C, 3; PCDH2; protocadherin gamma-C3; cadherin like 2; PC 43; PC43; PCDH GAMMA C3; protocadherin 2; protocadherin 43; PCDH 2; PCDHGC 3; Protocadherin gamma C3; Protocadherin gamma subfamily C 3; Protocadherin2; Protocadherin43; cadherin-like 2; protocadherin-2; protocadherin-43; OTTHUMP00000160013; PCDH-GAMMA-C3;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PCDHGC3-1572H Recombinant Human PCDHGC3, GST-tagged E.coli GST C-term-320aa
Human PCDHGC3-3385HCL Recombinant Human PCDHGC3 293 Cell Lysate HEK293 N/A
Human PCDHGC3-022H Active Recombinant Human PCDHGC3 Protein, His-tagged CHO Cell His
Chicken PCDHGC3-7145C Recombinant Chicken PCDHGC3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PCDHGC3 Related Research Area

PCDHGC3 involved in several pathways and played different roles in them. We selected most pathways PCDHGC3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCDHGC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PCDHGC3 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCDHGC3 itself. We selected most functions PCDHGC3 had, and list some proteins which have the same functions with PCDHGC3. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPLCD4;EPDL1;PCDH2G8;TTN;PPEF1;FREM2B;PCDHGA10;ADAMTS13;CABP1B

PCDHGC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCDHGC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCDHGC3.

NR4A1; HGD; MFSD3

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