PCF11
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Official Full Name
PCF11, cleavage and polyadenylation factor subunit, homolog
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Overview
PCF11 (pre-mRNA cleavage complex 2 protein) plays a role in transcriptional termination. The gene for PCF11 is also known as KIAA0824. -
Synonyms
PCF11; PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae); PCF11, cleavage and polyadenylation factor II subunit, homolog (S. cerevisiae); pre-mRNA cleavage complex 2 protein Pcf11; KIAA0824; PCF11p homolog; pre-mRNA cleavage comp;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PCF11-1573H | Recombinant Human PCF11, His-tagged | E.coli | His | 1206-1555aa | |
| Zebrafish | PCF11-1700Z | Recombinant Zebrafish PCF11 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
PCF11 involved in several pathways and played different roles in them. We selected most pathways PCF11 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA surveillance pathway | RBM8A;RNGTT;WDR33;GSPT1;PPP2CA;PPP2R1B;PPP2CB;PPP2R5E;PPP2R3A |
PCF11 has several biochemical functions, for example, RNA polymerase II core binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCF11 itself. We selected most functions PCF11 had, and list some proteins which have the same functions with PCF11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core binding | RECQL5;SMYD3;CDC73;WAC;CTR9;KIAA1967;SMYD2;PAF1;KIAA1530 |
| mRNA binding | IGF2BP2A;TYMS;D19BWG1357E;RBM25;RBM4;NOVA1;MRPL13;DHFR;MECP2 |
PCF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCF11.
Clp1; BNLF1; rpoB; q7ard3_yerpe; sSL2; trpE; sbcC3; AK1; Junb; USF1; MAPK3; CDK8; SNW1; EMC2; SAMD1; Cdkn2aip; MRPL50; CEP170P1; Rprd1b; CDKN2AIP
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