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PCOLCE2

  • Official Full Name

    procollagen C-endopeptidase enhancer 2

  • Overview

    Procollagen C-endopeptidase enhancer 2 is an enzyme that in humans is encoded by the PCOLCE2 gene.
  • Synonyms

    PCOLCE2; procollagen C-endopeptidase enhancer 2; PCPE2; Procollagen C proteinase enhancer 2; Procollagen COOH terminal proteinase enhancer 2; 2400001O18Rik; MGC187469; PCOLCE 2; PCOLE 2; PCPE 2; Procollagen C endopeptidase enhancer 2; Procollagen C-terminal proteinase enhancer protein 2; procollagen C-proteinase enhancer 2; procollagen COOH-terminal proteinase enhancer 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • HIS
  • His (Fc)
  • Avi
  • His|S
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PCOLCE2-1581H Recombinant Human PCOLCE2, GST-tagged E.coli GST 1-276aa
Human PCOLCE2-826H Recombinant Human PCOLCE2 Mammalian Cell His
Human PCOLCE2-150H Recombinant Human PCOLCE2 Protein, HIS-tagged E.coli HIS
Human PCOLCE2-1110H Recombinant Human PCOLCE2 protein, His & S-tagged E.coli His/S Cys154~Pro269 (Accession # Q9UKZ9)
Human PCOLCE2-3374HCL Recombinant Human PCOLCE2 293 Cell Lysate HEK293 N/A
Human PCOLCE2-3323H Recombinant Human PCOLCE2 protein, His-SUMO-tagged E.coli His-SUMO 24-415aa
Human PCOLCE2-3807H Recombinant Human PCOLCE2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PCOLCE2-4186H Recombinant Human PCOLCE2 Protein (Cys297-Cys415), N-His tagged E.coli N-His Cys297-Cys415
Human PCOLCE2-3807H-B Recombinant Human PCOLCE2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PCOLCE2 Related Articles

PCOLCE2 involved in several pathways and played different roles in them. We selected most pathways PCOLCE2 participated on our site, such as Collagen biosynthesis and modifying enzymes, Collagen formation, Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCOLCE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Collagen biosynthesis and modifying enzymesLEPRE1;COL19A1;COL5A3B;COL6A1;BMP1A;COL3A1;SERPINH1A;COL6A2;EMID2
Collagen formationCOL11A1B;COL19A1;COL28A1A;COL9A1B;COL4A4;CTSS;COL4A3;ADAMTS3;SERPINH1
Extracellular matrix organizationCOL9A1A;COL25A1;COL11A1B;TLL1;MFAP1B;CTSG;SERPINH1B;CTSK;ASPN

PCOLCE2 has several biochemical functions, for example, collagen binding, heparin binding, peptidase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PCOLCE2 itself. We selected most functions PCOLCE2 had, and list some proteins which have the same functions with PCOLCE2. You can find most of the proteins on our site.

Function Related Protein
collagen bindingACHE;SPARC;DDR1;C1QTNF1;PODN;VWF;CTSL1;SMAD7;HSD17B12
heparin bindingTGFBR3;CCL8;UBE4A;GM4980;SERPINA10;FGFR4;COL13A1;FGF9;SOST
peptidase activator activityPSME4B;PSME4;CLPX;PCOLCE;FN1;PINK1;PCOLCE2;APP;FBLN1

PCOLCE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCOLCE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCOLCE2.

Goldsmith, EC; Bradshaw, AD; et al. Cellular Mechanisms of Tissue Fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 304:C393-C402(2013).
Baicu, CF; Zhang, YH; et al. Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 303:H234-H240(2012).
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