PDS5A
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Official Full Name
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
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Overview
The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PDS5A; PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae); sister chromatid cohesion protein PDS5 homolog A; KIAA0648; PIG54; SCC 112; Cell proliferation inducing protein 54; KIAA0648.; sister chromatid cohesion protein 112; cell proliferation-inducing gene 54 protein; SCC112; SCC-112;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rat
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PDS5A-1628H | Recombinant Human PDS5A, GST-tagged | E.coli | GST | C-term-377aa | |
| Human | PDS5A-1565HCL | Recombinant Human PDS5A cell lysate | N/A |
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| Rat | PDS5A-4360R | Recombinant Rat PDS5A Protein | Mammalian Cell | His |
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| Rat | PDS5A-4020R-B | Recombinant Rat PDS5A Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | PDS5A-4020R | Recombinant Rat PDS5A Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | PDS5A-11226Z | Recombinant Zebrafish PDS5A | Mammalian Cell | His |
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| Chicken | PDS5A-1952C | Recombinant Chicken PDS5A | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
PDS5A involved in several pathways and played different roles in them. We selected most pathways PDS5A participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDS5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle | MCM7;SET;SETB;KIF2B;E2F2;YWHAB;CDC23;GORASP1;FAM175A |
| Cell Cycle, Mitotic | CDK4;NUMA1;BORA;CLASP1;CENPC1;PIANP;CDKN2A;SPC25;CTDNEP1A |
| Cohesin Loading onto Chromatin | NIPBL;PDS5B;NIPBLA;STAG2;MAU2;STAG1;NIPBLB;PDS5A;WAPAL |
| Establishment of Sister Chromatid Cohesion | ESCO1;STAG2;WAPAL;STAG1;PDS5B;CDCA5;ESCO2;PDS5A |
| M Phase | CENPI;NIPBLB;CENPL;SPC25;NDEL1B;MCPH1;CNEP1R1;CTDNEP1A;ARPP19 |
| Mitotic Anaphase | LEMD3;NSL1;VRK2;SKA2;CLIP1;CENPO;NUDC;TMPO;NDEL1 |
| Mitotic Metaphase and Anaphase | CENPI;RANGAP1B;SKA2;SPDL1;CENPL;NSL1;CDCA8;LEMD3;NDEL1B |
| Mitotic Prometaphase | CDCA5;CCDC99;NCAPH;NDEL1;PDS5A;SMC2;CENPI;NSL1;MLF1IP |
PDS5A has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDS5A itself. We selected most functions PDS5A had, and list some proteins which have the same functions with PDS5A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CHMP4C;SYT16;RASSF5;CROP;C19orf46;CREB5;PIN4;WLS;LOXL2 |
PDS5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDS5A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDS5A.
WAPAL; RAD21; SMC3; SMC1A
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