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PDS5B

  • Official Full Name

    PDS5, regulator of cohesion maintenance, homolog B

  • Overview

    This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.
  • Synonyms

    PDS5B; PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae); androgen induced proliferation inhibitor , APRIN; sister chromatid cohesion protein PDS5 homolog B; AS3; CG008; FLJ23236; KIAA0979; androgen-induced shutoff 3; androgen-induced pro;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human APRIN-728H Recombinant Human APRIN protein, GST-tagged Wheat Germ GST
Human PDS5B-1629H Recombinant Human PDS5B, His-tagged E.coli His C-term-302aa
Human PDS5B-101HCL Recombinant Human PDS5B cell lysate N/A
Human PDS5B-301643H Recombinant Human PDS5B protein, GST-tagged E.coli GST Met1139-Thr1310
Mouse PDS5B-12598M Recombinant Mouse PDS5B Protein Mammalian Cell His
Mouse PDS5B-6616M-B Recombinant Mouse PDS5B Protein Pre-coupled Magnetic Beads HEK293
Mouse PDS5B-6616M Recombinant Mouse PDS5B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken PDS5B-2053C Recombinant Chicken PDS5B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PDS5B involved in several pathways and played different roles in them. We selected most pathways PDS5B participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDS5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleMAPRE1;DCTN3;MCM4;MLF1IP;ESCO2;TFDP2;B9D2;ANAPC1;CEP76
Cell Cycle, MitoticCENPJ;ACTR1A;CEP290;NEK6;GINS4;ZWINT;E2F4;CDKN2D;CTDNEP1B
Cohesin Loading onto ChromatinNIPBLA;STAG2;WAPAL;STAG1;NIPBL;PDS5B;NIPBLB;MAU2;PDS5A
Establishment of Sister Chromatid CohesionSTAG2;ESCO2;ESCO1;WAPAL;PDS5A;STAG1;CDCA5;PDS5B
M PhaseKIF18A;NDEL1B;NDEL1A;MCPH1;ARPP19;SGOL2;MLF1IP;CCDC99;SETB
Mitotic AnaphasePDS5B;NSL1;NDEL1;ITGB3BP;ERCC6L;SKA1;KNTC1;CENPL;SPC24
Mitotic Metaphase and AnaphaseCENPN;ANKLE2;NUF2;ZWINT;CENPP;NDC80;ITGB3BP;CENPC1;INCENP
Mitotic PrometaphasePMF1;NCAPH;NCAPG;B9D2;CENPK;CENPI;ERCC6L;CDCA5;CDCA8

PDS5B has several biochemical functions, for example, ATP binding, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDS5B itself. We selected most functions PDS5B had, and list some proteins which have the same functions with PDS5B. You can find most of the proteins on our site.

Function Related Protein
ATP bindingUBE2D1A;IP6K2;SNRKA;PTK2B;CKMB;ABCG1;SMC2;SUCLG2;EPHB3
DNA bindingPREB;ARID1AA;ZNF689;ZNF597;TFPT;ZBTB16;FOXN1;ZSCAN4C;TCEANC2
protein bindingSFPI1;CACNA1SB;DDX39B;KBTBD6;GPI1;CCDC112;ACE;BCL11B;PDZD11

PDS5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDS5B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDS5B.

RAD21; SMC3; WAPAL

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