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PDYN

  • Official Full Name

    prodynorphin

  • Overview

    The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
  • Synonyms

    PDYN; prodynorphin; ADCA; PENKB; SCA23; proenkephalin-B; rimorphin; leumorphin; leu-enkephalin; preprodynorphin; preproenkephalin B; beta-neoendorphin-dynorphin; neoendorphin-dynorphin-enkephalin prepropeptide;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDYN-31089TH Recombinant Human PDYN Wheat Germ N/A 50 amino acids
Human PDYN-149H Recombinant Human PDYN Mammalian Cell His
Human PDYN-3316HCL Recombinant Human PDYN 293 Cell Lysate HEK293 N/A
Human PDYN-3825H Recombinant Human PDYN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PDYN-3825H-B Recombinant Human PDYN Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PDYN-3365R Recombinant Rhesus monkey PDYN Protein, His-tagged Mammalian Cell His
Rhesus Macaque PDYN-3183R Recombinant Rhesus Macaque PDYN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PDYN-3183R-B Recombinant Rhesus Macaque PDYN Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PDYN-241Z Recombinant Zebrafish PDYN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PDYN Related Articles

PDYN involved in several pathways and played different roles in them. We selected most pathways PDYN participated on our site, such as Cocaine addiction, Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDYN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cocaine addictionCREB3L1;GNAI3;CDK5;CREB3L3;DLG4;DRD1;CREB3L2;DRD2;PRKACG
AlcoholismNTRK2;HDAC9;HIST1H3A;HAT1;PPP1CC;GNG13;GNG4;HIST1H2BE;SLC6A3

PDYN has several biochemical functions, for example, opioid peptide activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDYN itself. We selected most functions PDYN had, and list some proteins which have the same functions with PDYN. You can find most of the proteins on our site.

Function Related Protein
opioid peptide activityZFP106;PENK;PNOC;PDYN;CDC42EP2

PDYN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDYN here. Most of them are supplied by our site. Hope this information will be useful for your research of PDYN.

Reed, B; Fang, N; et al. CHROMATIN ALTERATIONS IN RESPONSE TO FORCED SWIMMING UNDERLIE INCREASED PRODYNORPHIN TRANSCRIPTION. NEUROSCIENCE 220:109-118(2012).
Hanrieder, J; Ljungdahl, A; et al. L-DOPA-induced Dyskinesia is Associated with Regional Increase of Striatal Dynorphin Peptides as Elucidated by Imaging Mass Spectrometry. MOLECULAR & CELLULAR PROTEOMICS 10:-(2011).
  • Q&As
  • Reviews

Q&As (7)

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What is the impact of PDYN on neuroplasticity and learning processes? 11/11/2022

PDYN impacts neuroplasticity and learning, playing a role in memory formation and cognitive processes.

How does PDYN (Prodynorphin) modulate pain perception and the opioid system in the brain? 06/14/2022

PDYN, through its opioid peptides, plays a crucial role in modulating pain perception and opioid receptor activity.

How do alterations in PDYN expression or function affect sleep regulation and circadian rhythms? 12/01/2020

Changes in PDYN can affect sleep patterns and circadian rhythms, influencing sleep quality and regulation.

How does PDYN influence mood disorders, such as depression and anxiety? 11/27/2019

PDYN is linked to mood regulation, and its dysregulation can contribute to depression and anxiety.

How does PDYN contribute to addiction and substance abuse disorders? 10/04/2019

PDYN contributes to addiction and substance abuse by influencing reward pathways in the brain.

What are the mechanisms by which PDYN modulates the immune system and inflammatory responses? 10/22/2018

PDYN has a role in modulating immune responses and inflammation, impacting overall immune health.

What role does PDYN play in stress response and emotional regulation? 03/25/2018

PDYN is involved in stress response and emotional regulation, affecting the body's reaction to stressors.

Customer Reviews (3)

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Reviews
08/14/2020

    Swift protein expression optimization, invaluable for our research efficiency.

    04/08/2020

      Great antibody validation, enhances our immunoprecipitation experiments.

      04/21/2018

        Accurate protein structural characterization, vital for our investigations.

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