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PELI1

  • Official Full Name

    pellino E3 ubiquitin protein ligase 1

  • Synonyms

    PELI1;pellino E3 ubiquitin protein ligase 1;8827;ENSG00000197329;2p13.3;MGC50990, DKFZp686C18116;E3 ubiquitin-protein ligase pellino homolog 1;E3 ubiquitin-protein ligase pellino homolog 1;pellino-1;pellino homolog 1;protein pellino homolog 1;pellino-related intracellular-signaling molecule;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PELI1-1641H Recombinant Human PELI1, GST-tagged E.coli GST C-term-125aa
Human PELI1-659H Recombinant Human PELI1 Protein, His&GST-tagged Insect Cell His/GST
Human PELI1-1255H Recombinant Human PELI1 Mammalian Cell His
Human PELI1-3304HCL Recombinant Human PELI1 293 Cell Lysate HEK293 N/A
Human PELI1-5917H Recombinant Human PELI1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PELI1-1768HFL Recombinant Full Length Human PELI1 Protein, C-Flag-tagged Mammalian cells Flag
Human PELI1-2335H Recombinant Human PELI1 protein, His-tagged Insect Cell His 1-418aa
Human PELI1-4742H Recombinant Human PELI1 protein, His-tagged E.coli His 1-418aa
Human PELI1-1646H-B Recombinant Human PELI1 Protein Pre-coupled Magnetic Beads HEK293
Human PELI1-1646H Recombinant Human PELI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PELI1-4743H Recombinant Human PELI1 protein, GST-tagged E.coli GST 1-418aa
Mouse Peli1-4790M Recombinant Mouse Peli1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque PELI1-3370R Recombinant Rhesus monkey PELI1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PELI1-3188R Recombinant Rhesus Macaque PELI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PELI1-3188R-B Recombinant Rhesus Macaque PELI1 Protein Pre-coupled Magnetic Beads HEK293
Chicken PELI1-2090C Recombinant Chicken PELI1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PELI1 Related Articles

PELI1 involved in several pathways and played different roles in them. We selected most pathways PELI1 participated on our site, such as Activated TLR4 signalling, Cytokine Signaling in Immune system, IRAK1 recruits IKK complex, which may be useful for your reference. Also, other proteins which involved in the same pathway with PELI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activated TLR4 signallingALCAMB;CREB1;TNIP2;PELI1;CHST13;PELI2;TICAM1;MAP3K8;SAA1
Cytokine Signaling in Immune systemTRIM45;GBP5;NOD1;CASPB;CSK;IL1RN;EDAR;EDA;RASGRP4
IRAK1 recruits IKK complexPELI2;PELI1;PELI3
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulationPELI1;PELI2;PELI3
Immune SystemPVRL2L;GRAP2A;RNF14;TRIM10;TRIM14;UFL1;TRIM48;BTLA;IFIT10
Innate Immune SystemDEFB125;FCN3;DEFB116;CASP2;C1rb;MASP2;DEFA1;AGER;TXNIP
Interleukin-1 signalingTNIP2;PELI1;PELI2;IRAK3;IL1RN;NOD1;PELI3
MyD88 cascade initiated on plasma membraneDHX9;PELI2;S100A12;PELI1;TNIP2;TLR10;AGER;PELI3;DUSP3B

PELI1 has several biochemical functions, for example, ligase activity, protein binding, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PELI1 itself. We selected most functions PELI1 had, and list some proteins which have the same functions with PELI1. You can find most of the proteins on our site.

Function Related Protein
ligase activityPJA1;MYLIPB;RNF25;STUB1;LNX1;TRIM62;RING1;RCHY1;TNFAIP3
protein bindingTRPC2;C7orf31;PUM2;PKN3;SMYD1;HOXB5;NGDN;IRS1;ETL4
ubiquitin protein ligase activityG2E3;RNF4;NEDD4L;HERC5;HLTF;RNF121;UBE2G1;RNF13;TRIM71

PELI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PELI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PELI1.

IRAK1; VAC14; TRIP13; IRAK4; UBA1; UBE2N; SRPK2; UBE2V1; SRPK1; Rel; TFAP2A; IRS1; TRAF6

Giegerich, AK; Kuchler, L; et al. Autophagy-dependent PELI3 degradation inhibits proinflammatory IL1B expression. AUTOPHAGY 10:1937-1952(2014).
Park, HY; Go, H; et al. Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination. JOURNAL OF CLINICAL INVESTIGATION 124:4976-4988(2014).
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