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PIGN

Official Full Name

phosphatidylinositol glycan anchor biosynthesis, class N
Overview

This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported.
Synonyms

PIGN; phosphatidylinositol glycan anchor biosynthesis, class N; phosphatidylinositol glycan, class N; GPI ethanolamine phosphate transferase 1; MDC4; PIG N; MCD4 homolog; phosphatidylinositol-glycan biosynthesis class N protein; MCD4; MCAHS; PIG-N; MCAHS1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PIGN-778H	Recombinant Human PIGN	Mammalian Cell	His		Inquiry
Human	PIGN-1707H	Recombinant Human PIGN, GST-tagged	E.coli	GST	26-334aa	$319 / 25ug
Human	PIGN-3196HCL	Recombinant Human PIGN 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PIGN-3855H-B	Recombinant Human PIGN Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	PIGN-3855H	Recombinant Human PIGN Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	PIGN-6811Z	Recombinant Zebrafish PIGN	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PIGN involved in several pathways and played different roles in them. We selected most pathways PIGN participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	PIGP;PIGM;DPM2;PIGC;PIGH;PIGL;GPLD1;PIGV;PIGN
Metabolic pathways	ALDOA;CHSY3;ctaG;ATP6V1E1B;ADKA;POLR3B;ACSL1A;MTHFD1;STT3B

PIGN has several biochemical functions, for example, mannose-ethanolamine phosphotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGN itself. We selected most functions PIGN had, and list some proteins which have the same functions with PIGN. You can find most of the proteins on our site.

Function	Related Protein
mannose-ethanolamine phosphotransferase activity	PIGN;PIGO

PIGN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGN here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGN.

FJX1; Unc93b1