pik3c2g
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  • Official Full Name
  • phosphoinositide-3-kinase, class 2, gamma polypeptide
  • Background
  • The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.
  • Synonyms
  • PIK3C2G; phosphoinositide-3-kinase, class 2, gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma; phosphoinositide 3-kinase-C2-gamma; ph
Cat.#:PIK3C2G-165HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human PIK3C2G protein, GST-tagged, Active
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Cat.#:PIK3C2G-12799MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PIK3C2G Protein
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Cat.#:PIK3C2G-4459RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PIK3C2G Protein
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Cat.#:PIK3C2G-1453HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PIK3C2G (Active), GST-tagged
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Involved Pathway

PIK3C2G involved in several pathways and played different roles in them. We selected most pathways PIK3C2G participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3C2G were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Inositol phosphate metabolism
INPPL1A; ALDH6A1; PIP5KL1; NUDT10; INPP5E; TPI1B; MIOX; PIP5K1AA; INPP5K; PLCD3
Metabolic pathways
PTGIS; TYMP; MGAT1; TPI1B; GAA; FUT5; QARS; DNMT3AA; ALPI.2; PTGES
Phosphatidylinositol signaling system
PRKCA; MTMR1A; INPP5L; CALM2; CDS2; INPP5B; CALM3B; MTMR7; PLCD1B; PLCD3

Protein Function

PIK3C2G has several biochemical functions, for example, 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3C2G itself. We selected most functions PIK3C2G had, and list some proteins which have the same functions with PIK3C2G. You can find most of the proteins on our site.
Function
Related Protein
Function 1-phosphatidylinositol-3-kinase activity
Related Protein ATM; PIK3CD; PIK3C2B; PIK3CB; PIK3R3; PIK3CG; PIK3C2A; PIK3CA; PIK3C3; PIK3C2G
Function 1-phosphatidylinositol-4-phosphate 3-kinase activity
Related Protein PIK3C2B; PIK3CD; PIK3CA; PIK3C2G; PIK3CG; PIK3C2A; PIK3CB
Function ATP binding
Related Protein ACTG1; SMC1A; SCN8A; NTRK3A; MKNK2B; DDX4; MAP3K14; KATNA1; EPHA3; CLCN4-2
Function phosphatidylinositol binding
Related Protein SNX8; ING2; MYO1E; RPS6KC1; TULP4A; FCHO2; SNX19A; NOXO1; NCF1; SGK3
Function phosphatidylinositol phosphate kinase activity
Related Protein PIP5K1BA; PIP5K1BB; PIP5K1AA; PIP5K2; PIK3C2G; PIP5K1AB