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Pilra

  • Official Full Name

    paired immunoglobin-like type 2 receptor alpha

  • Overview

    Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.
  • Synonyms

    PILRA; paired immunoglobin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha; FDF03; Cell surface receptor FDF03; Inhibitory receptor PILR-alpha; paired immunoglobulin-like receptor alpha; PILRA_HUMAN; paired immunoglobulin-like type 2 receptor alpha; PILRA; cell surface receptor FDF03; inhibitory receptor PILR-alpha; paired immunoglobulin-like receptor alpha; paired immunoglobin-like receptor alpha; OTTHUMP00000207544; OTTHUMP00000207543; OTTHUMP00000207542; OTTHUMP00000207541; inhibitory receptor PILRalpha;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • Human Cell
  • Mammalian cells
  • C
  • hFc
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PILRA-513H Active Recombinant Human PILRA, His-tagged Mammalian cells His
Human PILRA-362H Recombinant Human PILRA Human Cell N/A Met1-Asp226
Human PILRA-578H Recombinant Human PILRA Protein, His-tagged HEK293 His
Human PILRA-363H Recombinant Human PILRA protein(Met1-Asp226), hFc-tagged HEK293 C-hFc Met1-Asp226
Human PILRA-001HCL Recombinant Human PILRA cell lysate Human Cell N/A
Human PILRA-002HCL Recombinant Human PILRA cell lysate Human Cell N/A
Human PILRA-3864H-B Recombinant Human PILRA Protein Pre-coupled Magnetic Beads HEK293
Human PILRA-3864H Recombinant Human PILRA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PILRA-4231H Recombinant Human PILRA Protein (Met1-Asp226), C-His tagged Mammalian cells C-His Met1-Asp226
Mouse Pilra-840M Active Recombinant Mouse Pilra Protein, His-tagged Mammalian cells His Leu21-Val197
Mouse Pilra-3358M Active Recombinant Mouse Pilra protein(Met1-Val197), His-tagged HEK293 C-His Met1-Val197
Mouse PILRA-2287MCL Recombinant Mouse PILRA cell lysate Human Cell N/A
Mouse Pilra-6742M Recombinant Mouse Pilra Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pilra-6742M-B Recombinant Mouse Pilra Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Pilra Related Research Area

Pilra involved in several pathways and played different roles in them. We selected most pathways Pilra participated on our site, such as Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pilra were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Herpes simplex infectionBMA2;H2-AB1;PML;CDK1;PPP1CA;HLA-DPB1;HLA-DRB4;SRSF5B;POU2F3

Pilra has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Pilra itself. We selected most functions Pilra had, and list some proteins which have the same functions with Pilra. You can find most of the proteins on our site.

Function Related Protein

Pilra has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pilra here. Most of them are supplied by our site. Hope this information will be useful for your research of Pilra.

gB; PTPN6; DNPH1; rseA; SORBS1; vglh_hhv1f_protein

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