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PITPNM3

Official Full Name

PITPNM family member 3
Overview

This gene encodes a member of a family of membrane-associated phosphatidylinositol transfer domain-containing proteins. The calcium-binding protein has phosphatidylinositol (PI) transfer activity and interacts with the protein tyrosine kinase PTK2B (also known as PYK2). The protein is homologous to a Drosophila protein that is implicated in the visual transduction pathway in flies. Mutations in this gene result in autosomal dominant cone dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

PITPNM3; PITPNM family member 3; membrane-associated phosphatidylinositol transfer protein 3; NIR1; RDGBA3; CORD5; Membrane associated phosphatidylinositol transfer protein 3; MGC157740; MGC157741; NIR 1; Phosphatidylinositol transfer protein, membrane-associated 3; PITPnm 3; PITPNM; PYK2 N terminal domain interacting receptor 1; PYK2 N-terminal domain-interacting receptor 1; retinal degeneration B alpha 3; NIR-1;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Insect Cell
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PITPNM3-12H	Recombinant Human PITPNM3 protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	PITPNM3-1735H	Recombinant Human PITPNM3, GST-tagged	E.coli	GST	472-544aa	$319 / 25ug
Human	PITPNM3-6484H	Recombinant Human PITPNM3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	PITPNM3-4790H	Recombinant Human PITPNM3 protein, His&Myc-tagged	E.coli	His&Myc	387-597aa	Inquiry
Human	PITPNM3-5847H	Recombinant Human PITPNM3 protein, His&Myc-tagged	Insect Cell	His&Myc	387-597aa	Inquiry
Mouse	PITPNM3-12847M	Recombinant Mouse PITPNM3 Protein	Mammalian Cell	His		Inquiry
Mouse	PITPNM3-6767M-B	Recombinant Mouse PITPNM3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Pitpnm3-4882M	Recombinant Mouse Pitpnm3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	PITPNM3-6767M	Recombinant Mouse PITPNM3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PITPNM3 Related Articles

PITPNM3 involved in several pathways and played different roles in them. We selected most pathways PITPNM3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PITPNM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PITPNM3 has several biochemical functions, for example, calcium ion binding, lipid binding, phosphatidylinositol transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PITPNM3 itself. We selected most functions PITPNM3 had, and list some proteins which have the same functions with PITPNM3. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	EMR2;BMP1A;ACTN4;PLA2G10;NINL;LPCAT2;DSG4;NOTCH1A;SULF2A
lipid binding	AP2M1A;MTTP;BPIFA5;PPARA;PAQR5A;SNX10A;TRIP10;PFN3;APOL4
phosphatidylinositol transporter activity	SCP2;PITPNBL;PITPNA;PITPNM3;PITPNM1;TNFAIP8L3;PITPNC1
protein binding	HDAC7;EVI5;TGM2;CUL1;ASNS;RPS6KA3;GPKOW;CD48;NUMB
receptor tyrosine kinase binding	DNAJA3;NRG3;ZNF259;ARHGEF16;SHC4;PTPN11;MYOC;PIK3R2;PTPN14

PITPNM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PITPNM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PITPNM3.

CCL18; q7chg5_yerpe; ligA; VAPA

Meng, FB; Li, W; et al. CCL18 promotes epithelial-mesenchymal transition, invasion and migration of pancreatic cancer cells in pancreatic ductal adenocarcinoma. INTERNATIONAL JOURNAL OF ONCOLOGY 46:1109-1120(2015).

He, CH; Su, SC; et al. Overexpression of PITPNM3 promotes hepatocellular carcinoma cell metastasis. CHINESE SCIENCE BULLETIN 59:1326-1333(2014).