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PITX3

  • Official Full Name

    paired-like homeodomain 3

  • Overview

    This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts.
  • Synonyms

    PITX3; paired-like homeodomain 3; paired like homeodomain transcription factor 3; pituitary homeobox 3; homeobox protein PITX3; PTX3; CTPP4; MGC12766;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Yeast
  • C
  • His
  • GST
  • GST|His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PITX3-645H Recombinant Human PITX3 Protein, GST-His-tagged E.coli GST/His
Human PITX3-3162HCL Recombinant Human PITX3 293 Cell Lysate HEK293 N/A
Human PITX3-2486H Recombinant Human PITX3 protein(21-90 aa), C-His-tagged E. coli C-His 21-90 aa
Mouse PITX3-12851M Recombinant Mouse PITX3 Protein Mammalian Cell His
Mouse PITX3-720M Recombinant Mouse PITX3 Protein (1-302 aa), GST-tagged E.coli GST 1-302 aa
Mouse PITX3-1484M Recombinant Mouse PITX3 Protein (1-302 aa), His-tagged Yeast His 1-302 aa
Mouse PITX3-6771M-B Recombinant Mouse PITX3 Protein Pre-coupled Magnetic Beads HEK293
Mouse PITX3-6771M Recombinant Mouse PITX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PITX3-4478R Recombinant Rat PITX3 Protein Mammalian Cell His
Rat PITX3-4138R-B Recombinant Rat PITX3 Protein Pre-coupled Magnetic Beads HEK293
Rat PITX3-4138R Recombinant Rat PITX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PITX3-11699Z Recombinant Zebrafish PITX3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PITX3 involved in several pathways and played different roles in them. We selected most pathways PITX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PITX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PITX3 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PITX3 itself. We selected most functions PITX3 had, and list some proteins which have the same functions with PITX3. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingZNF253;FLI1;GATA1;MYOD1;NFIA;NFATC4;GMEB1;ZNF92;ZNF264
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingFOS;PLAG1;EBF1;FOXJ2;POU4F2;PLSCR1;PAX5;PITX3;ZFAT

PITX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PITX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PITX3.

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