PLCB4
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Official Full Name
Plcb4 phospholipase C, beta 4
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Synonyms
PLCB4; phospholipase C, beta 4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; AI854601; A930039J07Rik; C230058B11Rik;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rat
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PLCB4-8265H | Recombinant Human PLCB4 protein, His & T7-tagged | E.coli | His/T7 | Ala2~Gln250 (Accession # Q15147) |
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| Human | PLCB4-3130HCL | Recombinant Human PLCB4 293 Cell Lysate | HEK293 | N/A |
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| Rat | PLCB4-4501R | Recombinant Rat PLCB4 Protein | Mammalian Cell | His |
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| Rat | PLCB4-4161R-B | Recombinant Rat PLCB4 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | PLCB4-4161R | Recombinant Rat PLCB4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Chicken | PLCB4-4303C | Recombinant Chicken PLCB4 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- PLCB4 Related Signal Pathway
PLCB4 involved in several pathways and played different roles in them. We selected most pathways PLCB4 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLCB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | PTENB;NUDT11;INPP5E;MTMR7B;PI4KAA;INPP4A;IMPA1;PLCH1;MINPP1 |
| Metabolic pathways | ACOX3;LPIN1;PGAM1A;NME4;CPOX;SUCLG1;MIBP;ADK;PLA2G5 |
| Rap signaling pathway | MET;FGF10;FGF20;PLCB2;VEGFA;PIK3R3;FGF19;MAGI1;NGFR |
| Calcium signaling pathway | PLCD1B;HTR2B;SLC8A1B;TACR3A;CACNA1G;CHRM5;GRM1;ATP2A2B;AGTR1B |
| cGMP-PKG signaling pathway | ATP1B3;PIK3CG;GATA4;GNAI3;MEF2C;ATP2A1;CREB3L1;ROCK1;VASP |
| Chemokine signaling pathway | CCL21;CCL1;PPBP;PIK3R1;CCR1L1;ARRB2;CXCL6;GNG4;GNG12 |
| Phosphatidylinositol signaling system | PLCG2;INPP5B;MTM1;PIK3R3;CDS2;DGKD;PIP4K2B;MTMR2;IPPK |
| Sphingolipid signaling pathway | PPP2R5E;CERS4;PPP2CB;MS4A2;ACER1;PIK3CD;PIK3R5;PPP2R2B;ABCC1 |
| Phospholipase D signaling pathway | PTK2B;SHC4;ARF6;MAP2K2;AGPAT3;PDGFRA;PLCB1;GRM5;MTOR |
| Adrenergic signaling in cardiomyocytes | AGTR2;ACTC1B;CACNG6;TNNT2A;CACNG8;CALM1B;AKT2L;ATF2;ATP2B2 |
| Vascular smooth muscle contraction | PPP1CA;MYL6;CALM2;GNA15.1;PLA2G2A;RAF1;CYP4A14;CALCRLA;RAF1A |
| Wnt signaling pathway | PSEN1;FZD8A;WNT9B;CUL1;PPP3R1B;PPP3CCB;WIF1;EP300;PRKCB |
| Gap junction | CSNK1DB;GRB2A;MAPK7;TUBB2A;HTR2C;TUBA4L;Adcy4;CDK1;PRKACAA |
| Platelet activation | ARHGEF1;ARHGEF12;MAPK1;STIM1;F2R;PIK3CB;P2RX1;TBXAS1;BTK |
| Circadian entrainment | RASD1;GNGT1;MTNR1B;PER3;PRKCA;GNAO1;GRIA2;GNAI3;PRKG1 |
| Long-term potentiation | GRIA2;CAMK2G;CALML3;CAMK2D;EP300;RPS6KA3;GRM1;RAP1B;PLCB1 |
| Retrograde endocannabinoid signaling | GNG2;GABRB1;PLCB1;GRM5;GRM1;GRIA4;GABRE;PLCB4;GNG8 |
| Glutamatergic synapse | PLCB3;PRKACB;SLC1A7;GRIN3B;GNG10;GNGT1;SLC1A6;GNAS;GNAI1 |
| Cholinergic synapse | CAMK2G;HRAS;NRAS;CHRNA4;CREB5;GNB3;KCNQ2;KCNQ3;KCNQ1 |
| Serotonergic synapse | PLCB1;PRKACB;SLC6A4;CYP2C50;PLA2G4D;HTR1A;BRAF;PLCB3;HTR3A |
| Dopaminergic synapse | ITPR1;PPP3CC;FOS;CALML3;AKT2;SLC6A3;PPP2R5D;ARRB2;CREB3L2 |
| Long-term depression | RYR1;GRID2;PLA2G4F;ITPR3;MAP2K2;ITPR1;NOS1;LYN;ARAF |
| Inflammatory mediator regulation of TRP channels | CALM2;PIK3R2;ASIC5;ASIC2;PLA2G4F;ITPR1;PLCB1;PPP1CC;SRC |
| Insulin secretion | GCG;PRKACB;CAMK2G;GIP;PRKCA;KCNMB2;CAMK2A;CREB3L3;STX1A |
| GnRH signaling pathway | MAPK10;CACNA1SB;GNRH2;CALM3B;MMP2;MAP3K4;PLD1A;PTK2BB;MAPK13 |
| Estrogen signaling pathway | MAP2K1;ATF6B;KCNJ6;PRKACG;GPR30;FOS;AKT2;GRB2;SHC1 |
| Melanogenesis | ADCY2B;KITLGA;CALM2B;CAMK2B;PRKCA;WNT3;CAMK2D2;MAPK1;FZD10 |
| Thyroid hormone synthesis | PDIA4;TG;ASGR2;LRP2;CREB3L1;ATP1B2;HSPA5;PRKCB;GPX5 |
| Thyroid hormone signaling pathway | MED12L;ITGAV;PLCE1;PFKP;PIK3R5;ESR1;MED12;MED24;RHEB |
| Oxytocin signaling pathway | MYLK4;PPP1R12C;CACNB4;PLCB1;CAMK2B;HRAS;KRAS;CCND1;GNAI1 |
| Renin secretion | ITPR1;CLCA1;GNAI1;AQP1;ORAI1;PDE3A;PRKACB;AGTR1A;PDE1B |
| Aldosterone synthesis and secretion | HSD3B4;CAMK1;ADCY6;NETO2;PLCB2;Adcy4;PRKCG;PLCB3;CACNA1H |
| Endocrine and other factor-regulated calcium reabsorption | ATP2B1;PRKCB;PRKCA;KLK1B1;ESR1;ATP1A1;ATP1B4;PRKCG;PTH1R |
| Salivary secretion | LYZ1;PRH2;TRPV6;PLCB4;CST1;PRH1;CALM4;CAP18;MUC5B |
| Gastric acid secretion | GAST;HRH2;PRKACB;CAMK2B;KCNK10;CALML3;ATP1A3;CA2;GNAQ |
| Pancreatic secretion | FXYD2;CELA2B;CPA1;KCNMA1;SLC4A4;CLCA2;ATP1A4;ATP1B1;ATP1A1 |
| Alzheimers disease | COX7A2L;PLCB1;BID;NDUFA4;UQCRC2;COX6A1;APBB1;NDUFS6;UQCR11 |
| Huntingtons disease | NDUFC1;UQCR10;UQCRC1;COX5B;COX6B1;NDUFB4;UQCRQ;COX8C;PPARG |
| Chagas disease (American trypanosomiasis) | TGFBR1;MAPK8;MAPK3;IL1B2;PLCB3;CCL3L1;IL12A;NOS2;TGFB1 |
| African trypanosomiasis | HBB-B2;IDO1;PRKCB;ICAM1;IL1B2;HBA2;HBA1;FAS;PRKCA |
| Amoebiasis | TLR2;RAB7A;PTK2;ACTN4;LAMA5;HSPB1;IL1R2;NFKB1;COL5A1 |
| Pathways in cancer | FGFR1;RUNX1;NKX3;CASP8;WNT9B;VEGFB;WNT5A;LAMB4;FZD9 |
PLCB4 has several biochemical functions, for example, calcium ion binding, mitogen-activated protein kinase binding, phosphatidylinositol phospholipase C activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLCB4 itself. We selected most functions PLCB4 had, and list some proteins which have the same functions with PLCB4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | CIB3;CDH10A;CALB1;MAN1A2;CALR3;MGMT;CALB2B;PCDH2AB11;ELTD1 |
| mitogen-activated protein kinase binding | TPR;NBR1;GTF2I;DUSP2;ACE;MAPK7;TNIP1;PLCB4;MAPKAPK2 |
| phosphatidylinositol phospholipase C activity | PLD4;PLCB4;CCR5;PLCB2;C3AR1;PLCD1;PLCD3A;CCR1;PLCZ1 |
| phospholipase C activity | PLCH2;PLCE1;PLCB3;PDIA3;PLCL1;PLCB2;PLCG2;ADORA1;PLCB4 |
| protein binding | SLC22A7;PIAS1;RTDR1;DYRK1B;IRF2;AUP1;HINT2;Il4ra;CRY1A |
| signal transducer activity | TAAR14A;TAAR12B;GNG13B;GNG10;VMN1R54;ITGB3BP;EXORH;ADORA2AA;OLFR5 |
PLCB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLCB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLCB4.
REL; GRIN1
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