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PLEKHG2

Official Full Name

pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms

PLEKHG2; pleckstrin homology domain containing, family G (with RhoGef domain) member 2; pleckstrin homology domain-containing family G member 2; ARHGEF42; CLG; FLJ00018; FLJ22458; Pleckstrin homology domain containing family G member 2; PH domain-containing family G member 2; common-site lymphoma/leukemia guanine nucleotide exchange factor;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PLEKHG2-1375HCL	Recombinant Human PLEKHG2 cell lysate		N/A		Inquiry
Human	PLEKHG2-2747H	Recombinant Human PLEKHG2 protein, His-tagged	E.coli	His	284-368 aa	$319 / 25ug

Involved Pathway
Protein Function
Interacting Protein

PLEKHG2 involved in several pathways and played different roles in them. We selected most pathways PLEKHG2 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE, G alpha (12/13) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEKHG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell death signalling via NRAGE, NRIF and NADE	BCL2L11;ARHGEF18;ITSN1;ARHGAP4A;KALRN;ARHGEF1A;FGD2;AATF;TRIO
G alpha (12/13) signalling events	TRIO;ARHGEF1A;FGD4;TIAM2;ADRA1B;FGD2;FGD4A;ADRA1D;ECT2
GPCR downstream signaling	GRP;RGS20;KISS1;GPR132;ANXA1;ABR;PROK1;ABHD12;RHOAE
NRAGE signals death through JNK	NET1;ARHGEF3;ARHGEF18;ABR;ARHGAP4;ECT2;DCLRE1B;ARHGAP4A;ARHGEF18A
Rho GTPase cycle	ARHGAP17B;FAM13B1;ARAP1;ARHGAP44;ARHGAP1;ARHGAP23;ARHGEF16;FAM13A;TAGAPA
Signal Transduction	NET1;OPN1LW2;OTULINB;ARHGAP15;RDH14B;UTS2D;OR7D2;NPSR1;DTX2
Signaling by GPCR	OR56A1;OR10A5;PTHRP2;NMBA;GPR39;OXGR1A.1;PTH;GPR18;RGS20
Signaling by Rho GTPases	DEPDC1B;ARHGEF16;RHOT1A;FGD2;TAGAPA;ARHGAP32;ARHGAP17A;PRC1;TAGAP1

PLEKHG2 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHG2 itself. We selected most functions PLEKHG2 had, and list some proteins which have the same functions with PLEKHG2. You can find most of the proteins on our site.

Function	Related Protein
Rho guanyl-nucleotide exchange factor activity	PLEKHG7;MCF2L;ARHGEF15;RASGRF2B;ARHGEF6;ARHGEF2;NET1;ARHGEF33;ARHGEF1
protein binding	LYL1;MPPE1;GCET2;HNF4A;VAMP1;S100A10;POLD3;SMARCD1;PTPN6

PLEKHG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHG2.

dxs; mexB; inhA