plekhg6
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  • Official Full Name
  • pleckstrin homology domain containing, family G (with RhoGef domain) member 6
  • Synonyms
  • PLEKHG6; pleckstrin homology domain containing, family G (with RhoGef domain) member 6; pleckstrin homology domain-containing family G member 6; FLJ10665; PH domain-containing family G member 6; myosin interacting guanine nucleotide exchange factor; myosi
Cat.#:PLEKHG6-2111HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PLEKHG6 Protein, MYC/DDK-tagged
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Cat.#:PLEKHG6-1784HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLEKHG6, His-tagged
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Cat.#:PLEKHG6-12959MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PLEKHG6 Protein
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Involved Pathway

PLEKHG6 involved in several pathways and played different roles in them. We selected most pathways PLEKHG6 participated on our site, such as Regulation of RhoA activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEKHG6 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Regulation of RhoA activity
ARHGAP9; ARHGEF28; ARHGEF3; ARAP1; ABR; OBSCN; ECT2; MYO9B; AKAP13; DEF6

Protein Function

PLEKHG6 has several biochemical functions, for example, GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHG6 itself. We selected most functions PLEKHG6 had, and list some proteins which have the same functions with PLEKHG6. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activator activity
Related Protein ARHGAP25; ARHGAP32; ARHGEF6; EVI5L; RAP1GAP2B; GDI1; RABEP2; ARHGAP8; SH3BGRL3; RASA1
Function Rho guanyl-nucleotide exchange factor activity
Related Protein FGD; BCR; PLEKHG4; FGD1; RASGRF2B; FARP1; SOS1; QUO; ARHGEF7; ARHGEF10
Function protein binding
Related Protein GSG1L; CD22; FZD2; USP18; USP42; N4BP2L2; FRMD8; COG1; FAM161A; PPM1K

Interacting Protein

PLEKHG6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHG6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHG6.
CEP55