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PNN

Official Full Name

pinin, desmosome associated protein
Overview

Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5CAGGTG-3. Capable of reversing CTBP1-mediated transcription repression. Component of a splicing-dependent multiprotein exon jun
Synonyms

PNN; pinin, desmosome associated protein; pinin; memA; 140 kDa nuclear and cell adhesion-related phosphoprotein; Desmosome-associated protein; Domain-rich serine protein; DRS; DRS protein; DRSP; Melanoma metastasis clone A protein; Nuclear protein SDK3; PININ_HUMAN; SR like protein; SR-like protein; OTTHUMP00000178906; neutrophil protein; SDK3;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

HEK293
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PNN-30966TH	Recombinant Human PNN	Wheat Germ	N/A	100 amino acids	Inquiry
Human	PNN-3074HCL	Recombinant Human PNN 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	PNN-13036M	Recombinant Mouse PNN Protein	Mammalian Cell	His		Inquiry
Mouse	PNN-6885M	Recombinant Mouse PNN Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PNN-6885M-B	Recombinant Mouse PNN Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PNN-7688Z	Recombinant Zebrafish PNN	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PNN Related Articles

PNN involved in several pathways and played different roles in them. We selected most pathways PNN participated on our site, such as RNA transport, mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
RNA transport	NCBP2;EIF2S1B;EIF3C;PABPC1L2A;EEF1A1B;PNN;XPOT;EIF1B;GEMIN6
mRNA surveillance pathway	MSI2A;PPP2R5D;PAPOLB;CASC3;UPF3B;PABPC5;RBM8A;MAGOH;PPP1CAA

PNN has several biochemical functions, for example, DNA binding, poly(A) RNA binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PNN itself. We selected most functions PNN had, and list some proteins which have the same functions with PNN. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ELMSAN1A;EN2;ZFP92;EGR2B;NKX6.3;ZNF334;MNX2B;VOX;SUPV3L1
poly(A) RNA binding	DUS3L;MTPAP;MRPS5;PPIL4;ZAK;HNRNPF;NOLC1;DHX30;HMGN2
structural molecule activity	SEPT5;KRT32;KRT27;KRT96;COL15A1B;NGS;CLDN11A;LCE4A;MAP2

PNN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNN here. Most of them are supplied by our site. Hope this information will be useful for your research of PNN.

YWHAG; SNW1; Srek1; SNIP1; FOS; YWHAZ; RNPS1; SF3A2; NFKBIL1; narH; PDPK1; UBE2I; q5nem8_fratt; TOE1; VAMP8; MED19

Madinier, A; Quattromani, MJ; et al. Enriched Housing Enhances Recovery of Limb Placement Ability and Reduces Aggrecan-Containing Perineuronal Nets in the Rat Somatosensory Cortex after Experimental Stroke. PLOS ONE 9:-(2014).

Dick, G; Tan, CL; et al. Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains. JOURNAL OF BIOLOGICAL CHEMISTRY 288:27384-27395(2013).