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Pole4

  • Official Full Name

    polymerase (DNA-directed), epsilon 4, accessory subunit

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human POLE4-1831H Recombinant Human POLE4, His-tagged E.coli His 1-117aa
Human POLE4-3048HCL Recombinant Human POLE4 293 Cell Lysate HEK293 N/A
Mouse POLE4-13077M Recombinant Mouse POLE4 Protein Mammalian Cell His
Mouse POLE4-6909M Recombinant Mouse POLE4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse POLE4-6909M-B Recombinant Mouse POLE4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque POLE4-3509R Recombinant Rhesus monkey POLE4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque POLE4-3327R Recombinant Rhesus Macaque POLE4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque POLE4-3327R-B Recombinant Rhesus Macaque POLE4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Pole4 Related Articles

Pole4 involved in several pathways and played different roles in them. We selected most pathways Pole4 participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pole4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismADSSL;GUK1A;PDE7B;ZNRD1;PDE5A;NPR1A;NT5E;AMPD1;POLR1D
Pyrimidine metabolismUPB1;DPYS;NME1;POLA1;POLR2H;NT5C3L;CAD;NT5C2A;POLR2I
Metabolic pathwaysDHFRL1;HK1;FUT4;BHMT;QDPR;CYP51;PTGESL;EPHX2;NT5M
DNA replicationGINS2;MCM3L;RNASEH2C;DBF4;POLE4;POLD4;rnhA;POLE2;GINS1
Base excision repairAPEX2;HMGB1B;HMGB1A;PARP2;PCNA;NEIL3;LIG1;xthA;nth
Nucleotide excision repairPPIE;RFC4;GTF2H1;GTF2H5;GTF2H2C;INO80C;POLE2;INO80;TFPT
HTLV-I infectionH2-AA;ATF1;NFYB;PRKACB;WNT16;WNT9B;TBPL2;PIK3CD;IL1R1

Pole4 has several biochemical functions, for example, DNA binding, DNA-directed DNA polymerase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Pole4 itself. We selected most functions Pole4 had, and list some proteins which have the same functions with Pole4. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF286A;MXTX2;UBN2;ZNF227;IRX5B;RAD54B;TFEC;TADA2A;PQBP1
DNA-directed DNA polymerase activityCCDC111;POLK;POLD3;POLA1;POLE;MYBBP1A;CHRAC1;PAPD7;POLD1
protein bindingMAD2L1BP;ALAS1;CHRDL2;WDR24;GOLPH3;CNTF;POMGNT1;DRAP1;RAD1
protein heterodimerization activitySMAD1;MTTP;WHRN;SYT14;HIST1H2AL;H2AFJ;IL12B;ENO2;SMC1A

Pole4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pole4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Pole4.

NFYB; POLE3; ORF; HSPA13; UBE3A; POLE2; POLE

Abdelmohsen, K; Srikantan, S; et al. Growth Inhibition by miR-519 via Multiple p21-Inducing Pathways. MOLECULAR AND CELLULAR BIOLOGY 32:2530-2548(2012).
Park, IJ; Lee, BH; et al. Mixed Micellization of Sodium Dodecylbenzene Sulfonate with Polyoxyethylene Lauryl Ether Surfactants (POLE4 and POLE23) in n-Butanol Aqueous Solution. JOURNAL OF SURFACTANTS AND DETERGENTS 15:41-46(2012).
  • Q&As
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