polr2h
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  • Official Full Name
  • polymerase (RNA) II (DNA directed) polypeptide H
  • Background
  • This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.
  • Synonyms
  • POLR2H; polymerase (RNA) II (DNA directed) polypeptide H; DNA-directed RNA polymerases I, II, and III subunit RPABC3; RPB8; and III 17.1 kDa polypeptide; and III subunit ABC3; II; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I; hRPB8; RNA polymerases I; RPAB3_HUMAN; RPB17; RPB8 homolog; OTTHUMP00000210505; OTTHUMP00000210507; OTTHUMP00000210508; OTTHUMP00000210509; OTTHUMP00000210511; OTTHUMP00000210512; RNA polymerases I, II,; RPABC3; hsRPB8
Cat.#:POLR2H-556HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human polymerase (RNA) II (DNA directed) polypeptide H, His-tagged
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Cat.#:POLR2H-8509HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human POLR2H, GST-tagged
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Cat.#:POLR2H-13098MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse POLR2H Protein
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Cat.#:POLR2H-801CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus POLR2H Protein, His-tagged
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Cat.#:POLR2H-4862CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken POLR2H
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Cat.#:POLR2H-2374ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish POLR2H
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Cat.#:POLR2H-3031HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human POLR2H 293 Cell Lysate
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Involved Pathway

POLR2H involved in several pathways and played different roles in them. We selected most pathways POLR2H participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Purine metabolism
ADKA; PKMA; GC3; PDE1A; PDE5AB; PDE7A; NT5C3B; NME7; POLD1; PNP5B
Pyrimidine metabolism
POLR1A; POLR2D; DHODH; NT5E; POLR3D; PRIM2; CMPK2; UCKL1; POLR3E; udp
Metabolic pathways
MTMR8; POLR3K; ST6GALNAC6; DHDPSL; PANK1; CPOX; RIMKLA; KCNG4; ALOX5A; HADHA
RNA polymerase
POLR1E; POLR3K; POLR1B; POLR2B; POLR2H; POLR2J3; POLR1D; ZNRD1; POLR3A; POLR2F
Cytosolic DNA-sensing pathway
IFNA8; POLR3B; RIPK1L; PYCARD; POLR3G; NFKBIAB; IFNA14; IFNA21; POLR3D; IFNA7
Huntingtons disease
COX7C; ATP5H; DNAI2; DNAH11; NDUFA5; BBC3; Casp3; ATP5F1; PLCB2; COX8A
Epstein-Barr virus infection
POLR3C; ENTPD8; POLR2F; IRAK1; TP53; POLR2E; SNW1; HLA-DRA; ICAM1; PIK3R5

Protein Function

POLR2H has several biochemical functions, for example, DNA binding, contributes_to RNA polymerase I activity, contributes_to RNA polymerase II activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2H itself. We selected most functions POLR2H had, and list some proteins which have the same functions with POLR2H. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein EPAS1B; ZFP518A; PROX1B; MYPOP; PCXA; DEK; HIVEP2; ERCC3; LEMD3; ZBED2
Function contributes_to RNA polymerase I activity
Related Protein POLR1A; POLR2E; POLR2F; POLR2H; POLR1D; POLR1E; POLR2K; POLR1C; ZNRD1; TWISTNB
Function contributes_to RNA polymerase II activity
Related Protein POLR2H; POLR2B; POLR2K; POLR2A; POLR2J3; POLR2L; POLR2F; POLR2EB; POLR2J; POLR2C
Function contributes_to RNA polymerase III activity
Related Protein POLR2H; POLR3C; POLR3B; POLR3K; POLR1D; CRCP; POLR3E; POLR3F; POLR1C; POLR2F

Interacting Protein

POLR2H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2H here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2H.
MED19; MED26; EIF1B; NME2; CD40; IKBKE; NFKBIB; TRAF6; ubiG; ssdna_dtdg