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POLR2J3

  • Official Full Name

    polymerase (RNA) II (DNA directed) polypeptide J3

  • Overview

    DNA-directed RNA polymerase II subunit RPB11-b2, also known as POLR2J3, belongs to the eukaryotic RPB11 RNA polymerase subunit family. POLR2J (DNA-directed RNA polymerase II subunit J) exist as three variants POLR2J1 (RPB11-a), POLR2J2 (RPB11-b1), and POLR2J3 (RPB11-b2). POLR2J3 is DNA-dependent RNA polymerases that catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  • Synonyms

    POLR2J2; RPB11b1; RPB11b2;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human POLR2J3-7175H Recombinant Human POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3, His-tagged E.coli His 1-115aa
Human POLR2J3-2453H Recombinant Human POLR2J3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human POLR2J3-5216H Recombinant Human POLR2J3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein

POLR2J3 involved in several pathways and played different roles in them. We selected most pathways POLR2J3 participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2J3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismGMPR2;CANT1B;FHIT;NPR1;NT5C2A;APRT;ENTPD3;ZNRD1;PDE6H
Pyrimidine metabolismNME7;TK2;PRIM1;UMPS;CAD;NME5;NT5C3B;POLR3E;NT5C1B
Metabolic pathwaysDCTPP1;CYP2C70;HMGCRB;ADA;POLR2F;PKM;GLYCTK;COQ5;ACSM2
RNA polymerasePOLR2H;POLR2EB;POLR3K;POLR2I;POLR2J;POLR1C;POLR1A;POLR2L;POLR2F
Huntingtons diseaseDNAIC2;DNAH5;SLC25A6;VDAC3;NDUFB11;TBPL1;DNAHC8;VDAC2;NDUFB2
Epstein-Barr virus infectionFcer2a;HLA-DQA1;CD38;SPI1;PIK3CB;MAPK11;HLA-A;HSPA8;HLA-B

POLR2J3 has several biochemical functions, for example, DNA binding, contributes_to RNA polymerase II activity, protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2J3 itself. We selected most functions POLR2J3 had, and list some proteins which have the same functions with POLR2J3. You can find most of the proteins on our site.

Function Related Protein
DNA bindingHOXC11A;POU4F2;HOXA4A;ISL2A;CXXC1B;EGR1;OVOL2;ARID3B;ARID4A
contributes_to RNA polymerase II activityPOLR2B;POLR2J2;POLR2L;POLR2EB;POLR2H;POLR2A;POLR2J;POLR2C;POLR2J3
protein dimerization activityHER12;MAX;HES7;OLIG3;GRIN2A;SCXA;MXD4;SOHLH1;DERL3

POLR2J3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2J3 here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2J3.

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